Paper Details 
Original Abstract of the Article :
Clinical trials of dual regimen dolutegravir/lamivudine (DOL/3TC) demonstrated potent efficacy and favorable safety in both antiretroviral therapy-naïve and -experienced patients, but data on older people are lacking. We aimed to evaluate virological efficacy and safety of DOL/3TC in suppressed olde...See full text at original site
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引用元:
https://doi.org/10.1089/AID.2023.0046

データ提供:米国国立医学図書館(NLM)

Dolutegravir/Lamivudine: A Safe and Effective Regimen for Older People Living with HIV-1

This retrospective cohort study investigates the efficacy and safety of switching to dolutegravir/lamivudine (DOL/3TC) in virologically suppressed people living with HIV-1 aged over 65 years. It found that switching to DOL/3TC was associated with maintenance of virological control and good tolerability in this population, supporting the use of this dual regimen in older individuals. The study also highlights the potential for DOL/3TC to simplify treatment regimens and reduce drug-drug interactions in this age group.

DOL/3TC: A Promising Option for Older HIV-1 Patients

This study provides encouraging evidence for the use of DOL/3TC in older people living with HIV-1. The drug's ability to maintain virological control while simplifying treatment and reducing drug-drug interactions makes it a valuable option for this population. These findings contribute to the growing body of knowledge on effective and well-tolerated treatment options for older individuals with HIV-1.

Improving HIV-1 Treatment for Older Adults

This research offers valuable insights into the management of HIV-1 in older adults. By demonstrating the safety and efficacy of DOL/3TC in this population, the study contributes to the development of effective and personalized treatment strategies for aging individuals living with HIV-1. This knowledge can empower healthcare professionals to provide optimal care and support for older patients navigating the complexities of HIV-1 management.

Dr. Camel's Conclusion

This study offers a reassuring reminder that even in the desert of aging, there can be fertile oases of hope for individuals living with HIV-1. DOL/3TC provides a safe and effective treatment option for older patients, simplifying their regimens and minimizing potential complications. This research reinforces the importance of tailoring treatment strategies to the unique needs of aging individuals, ensuring optimal outcomes for this growing population.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-07-05
Further Info :

Pubmed ID

37335031

DOI: Digital Object Identifier

10.1089/AID.2023.0046

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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