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Clinical comparison of dipivalyl epinephrine and epinephrine in the treatment of glaucoma.

Author: HargettN A, KohnA N, MossA P, PodosS M, RitchR, SmithH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Dipivalyl epinephrine was less effective than epinephrine hydrochloride in decreasing intraocular pressure, but it was associated with significantly fewer side effects.
Paper Details　
Original Abstract of the Article :
Dipivalyl epinephrine, 0.1%, though slightly less effective in decreasing intraocular pressure, showed significantly fewer side effects than epinephrine hydrochloride, 2%. Seventeen patients with symmetrically increased intraocular pressures who completed a six-month double-masked crossover study sh...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9394(79)90142-9

データ提供：米国国立医学図書館（NLM）

Dipivalyl Epinephrine vs. Epinephrine: A Comparative Study in the Desert of Glaucoma Treatment

Glaucoma, a leading cause of blindness, is often treated with medications that lower intraocular pressure. This study compares the effectiveness and side effects of dipivalyl epinephrine and epinephrine hydrochloride in treating glaucoma. It's like comparing two different types of camels – one might be faster but less durable, while the other might be slower but more reliable.

A Search for the Optimal Solution

The study found that dipivalyl epinephrine, while slightly less effective than epinephrine in reducing intraocular pressure, had significantly fewer side effects. It's like choosing a camel that can navigate the desert with minimal risk of getting lost or injured. This research highlights the need for careful consideration of both efficacy and safety when choosing glaucoma treatments.

Balancing Benefits and Risks in Glaucoma Management

This study emphasizes the importance of individualized treatment approaches for glaucoma, taking into account both the benefits and risks of different medications. It's like selecting the right camel for a specific journey, considering the terrain and the cargo being carried. By understanding the unique characteristics of each medication, healthcare providers can make informed decisions to optimize patient outcomes.

Dr.Camel's Conclusion

This research provides valuable insights into the comparative efficacy and safety of dipivalyl epinephrine and epinephrine hydrochloride for glaucoma treatment. It highlights the importance of individualizing treatment approaches, considering both the effectiveness and potential side effects of medications. It's a reminder that navigating the desert of glaucoma management requires careful consideration of the unique needs and circumstances of each patient.

Date :
  1. Date Completed 1979-06-29
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

373450

DOI: Digital Object Identifier

10.1016/0002-9394(79)90142-9

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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