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Efficacy and safety of intravenous tranexamic acid in urologic surgery: A systematic review and meta-analysis of randomized controlled trials.

Author: ChenKuo-Tai, HsuChien-Chin, LeeKuo-Chang, LinYu-Hui

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intravenous Tranexamic acid (TXA) was found to reduce intraoperative blood loss, decrease the need for transfusion, and shorten operative time in patients undergoing urologic surgeries without increasing the risk of thromboembolic events.
Paper Details　
Original Abstract of the Article :
BACKGROUND: This meta-analysis compared the effects of intravenous Tranexamic acid (TXA) and a placebo on hemostasis, hospital course, and complications in adult patients undergoing various urologic surgeries. METHODS: The literature was extensively searched using various databases. The primary out...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289517/

データ提供：米国国立医学図書館（NLM）

Tranexamic Acid in Urologic Surgery: A New Oasis in the Desert of Hemostasis

Urology is a field of medicine that focuses on the intricate workings of the urinary tract and the male reproductive system. This study investigates the efficacy and safety of intravenous tranexamic acid (TXA) in urologic surgery, examining its impact on hemostasis, hospital course, and complications. The researchers conducted a systematic review and meta-analysis of randomized controlled trials to assess the benefits of TXA in this surgical setting.

Tranexamic Acid: A Potential Hemostatic Champion

The meta-analysis revealed that intravenous TXA effectively reduced intraoperative blood loss and the need for blood transfusions in patients undergoing urologic surgery. The study also found that TXA did not increase the risk of thromboembolic events, suggesting a favorable safety profile. Think of TXA as a powerful camel that can quickly navigate the treacherous desert of hemostasis, helping to control bleeding and ensure a smooth surgical journey.

Optimizing Hemostasis in Urologic Surgery

The study provides strong evidence supporting the use of intravenous TXA in urologic surgery. The researchers recommend its use as a valuable tool for reducing blood loss and improving surgical outcomes. This research offers a potential oasis in the desert of hemostasis, providing a valuable tool for urologists to enhance patient care.

Dr.Camel's Conclusion

This comprehensive meta-analysis provides compelling evidence for the effectiveness of intravenous TXA in urologic surgery. The researchers highlight its potential to improve hemostasis and minimize complications, offering a valuable tool for surgeons navigating the challenging terrain of urological procedures.

Date :
  1. Date Completed 2023-06-26
  2. Date Revised 2023-09-27
Further Info :

Pubmed ID

37352047

DOI: Digital Object Identifier

PMC10289517

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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