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Modulating effects of <i>Astragalus</i> polysaccharide on immune disorders via gut microbiota and the TLR4/NF-κB pathway in rats with syndrome of dampness stagnancy due to spleen deficiency.
Author: DuanChenchen, LiuXiumei, LiuYanli, LuGuangying, LyuQin, WangShijun, ZhaoHaijun, ZhaoWenxiao, ZhaoXuelian, ZhengJun
Original Abstract of the Article :
The syndrome of dampness stagnancy due to spleen deficiency (DSSD) is relatively common globally. Although the pathogenesis of DSSD remains unclear, evidence has suggested that the gut microbiota might play a significant role. <i>Radix Astragali</i>, used as both medicine and food, exerts the effect...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350370/
データ提供：米国国立医学図書館（NLM）
Astragalus Polysaccharide: A Desert Oasis for Immune Disorders
[Syndrome of dampness stagnancy due to spleen deficiency] (DSSD) is a condition characterized by a weakened spleen and an accumulation of dampness in the body. This can lead to various immune disorders. This study investigates the effects of Astragalus polysaccharide (APS) on the immune system and gut microbiota in DSSD rats, exploring its potential to alleviate these disorders. Think of the gut microbiota as a complex ecosystem in the desert, where different bacteria contribute to the overall health of the body.APS: A Journey to Balance
Researchers studied the impact of APS on DSSD rats, finding that it significantly improved body weight gain, immune organ indexes, and reduced inflammatory markers. APS also impacted the gut microbiota, increasing its diversity and changing its composition. This suggests that APS could be a valuable tool for restoring balance to the body's immune system and gut health. Imagine APS as a camel caravan, carrying valuable resources to restore balance to the desert ecosystem.A New Perspective on Immune Health
This research provides a compelling argument for the potential of APS in the treatment of immune disorders associated with DSSD. It's like a camel discovering a secret oasis in the desert, offering a path to restoration. This research could lead to new approaches for managing DSSD and improving the overall health of those affected by this condition.Dr. Camel's Conclusion
This study highlights the potential of APS as a valuable tool for restoring balance to the body's immune system. It's like a camel caravan traversing a desert landscape, leaving behind a trail of renewal and vitality. This research could lead to a new understanding of the gut-immune connection and the development of novel therapies for DSSD and other immune disorders.Date :
- Date Completed 2023-07-18
- Date Revised 2023-07-19
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