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Comparison of Intermittent and Continuous Androgen Deprivation Therapy in Prostate Cancer Patients: An Up-to-Date Meta-analysis for Urologists and Medical Providers.

Author: BeckerBenjamin, ReddyAnish, StroeverStephanie, de RieseWerner T W

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Hormone therapy (androgen deprivation therapy or ADT) has been used to treat advanced prostate cancer since the 1940s. While ADT has changed significantly over the years, it's still commonly used. While ADT is often given continuously, some people receive it intermittently. This review will examine research on the impact of continuous versus intermittent ADT on survival, including deaths from prostate cancer and other causes. The goal is to provide guidance on choosing the best approach for each person.
Paper Details　
Original Abstract of the Article :
Androgen deprivation therapy first became the treatment of choice for advanced prostate cancer in the 1940s with Charles Huggins' discoveries. Eight decades later, androgen deprivation therapy has significantly evolved, and yet is still utilized in various ways to treat certain forms of prostate can...See full text at original site
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引用元：
https://doi.org/10.1097/UPJ.0000000000000424

データ提供：米国国立医学図書館（NLM）

Androgen Deprivation Therapy: A New Frontier in Prostate Cancer Treatment

This research delves into the world of prostate cancer treatment, exploring the effectiveness of androgen deprivation therapy (ADT). This treatment, which has been around for decades, has evolved significantly since its inception. The authors conducted a meta-analysis to evaluate the effects of continuous and intermittent ADT on mortality rates in patients with prostate cancer. They focused on understanding the impact of ADT on prostate cancer-specific mortality and non-prostate cancer causes.

While continuous ADT has historically been the standard treatment, intermittent ADT has emerged as an alternative approach. This study provides an updated review of the evidence surrounding the efficacy of both approaches. The authors aimed to offer guidance to healthcare providers in choosing the appropriate form of ADT for their patients.

The Right Treatment for You

The study suggests that both continuous and intermittent ADT have their own benefits and drawbacks. The best treatment option for each patient will depend on individual factors such as the stage and severity of the cancer, potential side effects, and patient preferences.

Living with Prostate Cancer

Prostate cancer is a challenging diagnosis. This research highlights the advancements in treatment options available to patients. If you or someone you know is affected by prostate cancer, it's important to consult with a healthcare professional to develop a personalized treatment plan.

Dr. Camel's Conclusion

The study underscores the complexity of prostate cancer treatment. The evolution of ADT offers a diverse range of options for patients. Just as the desert is full of diverse landscapes, the world of prostate cancer treatment is continually changing. Stay informed, seek expert advice, and navigate this journey with hope.

Date :
  1. Date Completed 2023-08-21
  2. Date Revised 2023-09-08
Further Info :

Pubmed ID

37505912

DOI: Digital Object Identifier

10.1097/UPJ.0000000000000424

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Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

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