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Lemborexant levels in breast milk after single doses in healthy, lactating women.
Author: AluriJagadeesh, BrimhallDarin, ChengJocelyn Y, HallNancy, MolineMargaret, RawalSumit
Original Abstract of the Article :
AIMS: The aim of this study is to determine the cumulative amount of lemborexant (a competitive dual orexin receptor antagonist approved to treat adults with insomnia) excreted in human breast milk and the relative infant dose (RID) as a proportion of daily maternal dose. METHODS: E2006-A001-010 wa...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/bcp.15880
データ提供:米国国立医学図書館(NLM)
Lemborexant in Breast Milk: Navigating the Desert of Motherhood
Dr. Camel here, ready to address a topic that concerns many mothers: the safety of medications during breastfeeding. This study investigated the presence of lemborexant, a medication used to treat insomnia, in breast milk. The researchers wanted to determine the amount of lemborexant transferred to the infant through breast milk and assess its potential impact on the infant's health.
Lemborexant in Breast Milk: A Desert Oasis of Safety
The study found that trace amounts of lemborexant were detected in breast milk, but the levels were significantly low. Furthermore, the study reported that lemborexant was well tolerated by the lactating mothers. This is great news, like discovering a small, hidden spring in a vast desert! It suggests that lemborexant use by breastfeeding mothers is likely safe for their infants.
Lemborexant and Breastfeeding: Finding a Balance
While this study provides encouraging results, it's important to consult with a healthcare professional before taking any medication while breastfeeding. Remember, every mother's journey through the desert of motherhood is unique, and individual needs may vary. It's all about finding the right balance between the benefits and risks of medications, ensuring both the mother's well-being and the infant's safety.
Dr. Camel's Conclusion
This study offers a glimmer of hope for breastfeeding mothers seeking treatment for insomnia. It suggests that lemborexant can be used with relative safety while breastfeeding. However, it's essential to consult with a healthcare professional to make informed decisions about medication use during breastfeeding. Remember, the desert of motherhood is vast and often unpredictable, but with the right guidance and support, we can find our way to a safe and healthy oasis!
Date :
- Date Completed n.d.
- Date Revised 2023-08-24
Further Info :
Related Literature
English
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