[Fundamental and clinical studies of cefixime granules in pediatrics].

Author: AsaishiT, IshizukaY, IwataS, KumagaiN, KusanoS, KusumotoY, SaitoN, SatoY, SunakawaK, YokotaT

Paper Details 
Original Abstract of the Article :
Fundamental and clinical studies of cefixime (CFIX) granules, a new oral cephalosporin, were carried out with the following results: The MICs of CFIX against 234 clinical isolates were determined. Antibacterial activities of the drug against S. aureus, S. epidermidis and E. faecalis were weaker than...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3761536

データ提供:米国国立医学図書館(NLM)

Cefixime Granules: A New Weapon in the Pediatric Arsenal?

The world of pediatrics is constantly evolving, with new medications and treatments being developed to combat the unique challenges of childhood illnesses. This research dives into the realm of antibiotics, specifically exploring the effectiveness of cefixime granules in treating various bacterial infections in children. The study utilized a rigorous approach, encompassing both in vitro and in vivo assessments to understand the drug's antibacterial properties and pharmacokinetics.

The researchers discovered that cefixime, a new oral cephalosporin, effectively inhibits the growth of a wide range of bacteria commonly associated with pediatric infections. The study also revealed that cefixime granules exhibited a favorable safety profile, with minimal side effects observed. The results highlight the potential of cefixime granules as a valuable therapeutic option for pediatric infections, offering a safe and effective alternative to existing treatments.

A Promising Solution for Pediatric Infections

The research demonstrated that cefixime granules effectively eradicated a significant portion of bacterial strains associated with common pediatric infections. In 88% of the children treated, the drug yielded excellent to good clinical responses, signifying its effectiveness in combating various bacterial infections. This success underscores the potential of cefixime granules to become a valuable tool in the fight against childhood infections.

Safety and Efficacy: A Balancing Act

While cefixime granules showed promising efficacy, the researchers observed minor side effects, including diarrhea and soft stool in a small number of children. However, these symptoms resolved shortly after treatment completion, indicating that cefixime granules maintain a favorable safety profile. The study's findings emphasize the importance of carefully monitoring children for potential side effects while ensuring they receive the necessary treatment to combat infections effectively.

Dr.Camel's Conclusion

This study, like a shimmering oasis in a vast desert, sheds light on the potential of cefixime granules to provide a safe and effective solution for pediatric infections. While the research highlights the drug's promise, further studies are needed to delve deeper into its long-term effects and ensure its optimal use in the ever-evolving landscape of pediatric medicine. As a researcher, I find this study truly exciting! The findings offer a glimmer of hope for children battling infections, reminding us that innovation and exploration can lead to brighter futures.

Date :
  1. Date Completed 1986-10-30
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3761536

DOI: Digital Object Identifier

3761536

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PICO Info
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Languages

Japanese

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