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[Fundamental and clinical studies on cefixime in pediatric field].
Author: KidaK, MatsudaH, MiyazakiM, MuraseM
Original Abstract of the Article :
Cefixime (CFIX) was evaluated for pharmacokinetics, therapeutic effectiveness on infection, safety, and bacteriological effectiveness in pediatrics. The following is a summary of the results. Pharmacokinetics in 4 children, 2 each receiving a single dose of 1.5 mg or 6.0 mg per kg body weight, were ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/3761545
データ提供:米国国立医学図書館(NLM)
Cefixime: A Promising Antimicrobial for Pediatric Use
The world of pediatric medicine is a delicate balance, requiring a special understanding of the needs of young patients. This study explores the pharmacokinetics, therapeutic effectiveness, safety, and bacteriological effectiveness of cefixime in children. It's like carefully navigating a delicate sandcastle, ensuring that every aspect of the treatment is well-considered and safe for young patients.
Pharmacokinetic Studies in Children
The study involved pharmacokinetic evaluations in four children who received single doses of cefixime. The researchers meticulously measured serum concentrations and half-lives, providing valuable insights into how cefixime is absorbed, distributed, and eliminated in young bodies.
Therapeutic Effectiveness and Bacteriological Evaluation
The study also evaluated the therapeutic effectiveness of cefixime in 19 children with infections. The researchers observed excellent or good outcomes in all cases. They also conducted a bacteriological evaluation in 10 children, demonstrating the ability of cefixime to successfully eradicate pathogens.
Dr. Camel's Conclusion
This study offers valuable insights into the potential of cefixime as a safe and effective antimicrobial for pediatric use. The research highlights its impressive therapeutic effectiveness and provides valuable pharmacokinetic data. However, more research is needed to fully understand the long-term effects of cefixime in children.
Date :
- Date Completed 1986-10-30
- Date Revised 2016-11-16
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