Cimetidine in anastomotic ulceration after partial gastrectomy.

Author: DriessenW M, FestenH P, LamersC B, Van TongerenJ H

Paper Details 
Original Abstract of the Article :
In order to assess the efficacy of cimetidine in patients with endoscopically anastomotic ulcer after partial gastrectomy, 21 such patients entered a double-blind prospective clinical trial. At endoscopy after 4 wk of treatment, 8 of 12 patients treated with 1 g of cimetidine daily compared with 1 o...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/376390

データ提供:米国国立医学図書館(NLM)

Cimetidine: A Healing Oasis for Anastomotic Ulcers

The world of gastrointestinal health can be a complex and sometimes painful landscape. This study delves into the intricacies of anastomotic ulcers, a type of ulcer that can form after a partial gastrectomy, a surgical procedure to remove part of the stomach. The researchers investigated the efficacy of cimetidine, a medication that blocks histamine receptors in the stomach, for treating these ulcers. They conducted a double-blind prospective clinical trial involving 21 patients with anastomotic ulcers. The study found that after four weeks of treatment, eight out of twelve patients treated with cimetidine daily had healed ulcers, compared to only one out of nine patients who received a placebo. This statistically significant difference supports the effectiveness of cimetidine in healing anastomotic ulcers. The study also revealed that cimetidine significantly relieved symptoms associated with the ulcers. The healing rate after one month of treatment with cimetidine was 67% and increased to 86% after two months. The researchers found that cimetidine was effective in preventing relapse, as only three out of 19 patients experienced a recurrence during a year of maintenance therapy. Importantly, the study reported no serious side effects associated with cimetidine.

A Glimpse into the Healing Power of Cimetidine

This research provides a compelling argument for the effectiveness of cimetidine in treating anastomotic ulcers. The researchers' findings highlight the potential of cimetidine to promote healing and alleviate symptoms associated with these ulcers.

Navigating the Desert of Gastric Health

This study reminds us that even in the challenging landscape of gastrointestinal health, there are oasis of hope. The researchers' findings provide valuable insights for healthcare professionals and patients seeking effective treatments for anastomotic ulcers.

Dr. Camel's Conclusion

Imagine a camel caravan traversing a harsh desert, facing the perils of thirst and hunger. For those with anastomotic ulcers, cimetidine acts as a refreshing oasis, providing relief from the pain and discomfort. This study serves as a testament to the power of medication in healing and promoting well-being.

Date :
  1. Date Completed 1979-09-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

376390

DOI: Digital Object Identifier

S0016508579001116

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Languages

English

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