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Vaccines for preventing herpes zoster in older adults.

Author: AndrioloBrenda Ng, AndrioloRegis B, Canteiro CruzEduardo, GagliardiAnna Mz, PugaMaria Eduarda Dos Santos, TorloniMaria Regina, de Oliveira GomesJuliana

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This Cochrane Review provides an update on the effectiveness and safety of herpes zoster vaccines. Two types of vaccines are available: the single-dose live attenuated zoster vaccine (LZV) and the recombinant zoster vaccine (RZV).
Paper Details　
Original Abstract of the Article :
Herpes zoster, commonly known as shingles, is a neurocutaneous disease caused by the reactivation of the virus that causes varicella (chickenpox). After resolution of the varicella episode, the virus can remain latent in the sensitive dorsal ganglia of the spine. Years later, with declining immunity...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542961/

データ提供：米国国立医学図書館（NLM）

The Quest for Shingles Protection in Older Adults

The field of infectious disease research always seeks better ways to safeguard our health. This study focuses on herpes zoster, commonly known as shingles, a painful condition that can strike older adults. The researchers explore the effectiveness of different vaccines designed to prevent this debilitating disease. They delve into the mechanism of how these vaccines work, specifically focusing on the immune response they elicit. This study contributes to the ongoing effort to develop more effective and accessible vaccination strategies for older adults, helping them lead healthier and more comfortable lives.

A Deeper Dive into Vaccine Effectiveness

The study compared two types of herpes zoster vaccines: LZV, a single-dose live attenuated vaccine, and RZV, a recombinant vaccine. Both vaccines showed promising results in preventing shingles, but RZV demonstrated a higher level of efficacy. This finding suggests that RZV may be a more effective option for protecting older adults from this painful condition. It's a small step in the grand scheme, but it brings us closer to a world where shingles is less of a concern.

Protecting Ourselves from Shingles

Vaccination offers a powerful way to prevent shingles, a painful condition that can affect our quality of life. By receiving the recommended vaccines, we can arm our bodies with the tools they need to fight off this virus. It's a simple yet profound way to safeguard our health and well-being. The key takeaway? Prevention is the ultimate cure! So, let's embrace the power of vaccines and ensure a healthier future for ourselves and those we love.

Dr.Camel's Conclusion

This study reveals the importance of vaccination, especially for older adults, in preventing shingles. It's like building a protective sandcastle around ourselves, shielding us from the harsh realities of this painful condition. The findings underline the importance of vaccination, not just for personal health, but for the overall well-being of our community.

Date :
  1. Date Completed 2023-10-05
  2. Date Revised 2023-11-23
Further Info :

Pubmed ID

37781954

DOI: Digital Object Identifier

PMC10542961

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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