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Dasatinib-Associated Acneiform Eruption Successfully Treated With Sarecycline in a Patient With Chronic Myeloid Leukemia.

Author: DubinDanielle P, GulatiNicholas, PoplauskyDina, TremblayDouglas, YoungJade N

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

A case of a patient with chronic myeloid leukemia (CML) who developed an acneiform eruption after taking dasatinib is presented. The eruption was effectively treated with sarecycline, a narrow-spectrum tetracycline. Sarecycline is a potentially safer alternative to doxycycline, especially for long-term use.
Paper Details　
Original Abstract of the Article :
Dasatinib is a second-generation tyrosine inhibitor that is used for the treatment of patients with chronic myeloid leukemia (CML). It can cause a myriad of skin toxicities, including pruritis, pigmentary abnormalities of hair and skin, and maculopapular rashes. Rarely, it can be associated with acn...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590148/

データ提供：米国国立医学図書館（NLM）

Dasatinib-Associated Acneiform Eruption: A Desert of Skin Reactions

The desert of skin reactions can be a challenging landscape, often requiring specialized treatment and management. This study presents a case report of a patient with chronic myeloid leukemia (CML) who developed an acneiform eruption associated with dasatinib, a tyrosine kinase inhibitor used to treat CML. Researchers discuss the various skin toxicities associated with dasatinib and explore the successful treatment of this acneiform eruption with sarecycline, a narrow-spectrum tetracycline. This study highlights the importance of recognizing and effectively managing skin reactions associated with medications.

A Hidden Oasis: Sarecycline as a Treatment for Acneiform Eruption

This case report provides a potential oasis in the desert of dasatinib-associated acneiform eruption. Sarecycline, a targeted tetracycline, offers a promising alternative treatment option with an improved safety profile.

Navigating the Desert of Skin Reactions: Practical Implications for Everyday Life

This research emphasizes the importance of reporting any skin reactions to medications to your healthcare provider. Early detection and appropriate treatment are essential for managing skin reactions and minimizing their impact on quality of life.

Dr.Camel's Conclusion

This case report provides a valuable example of how to effectively manage skin reactions associated with medications. It highlights the potential of sarecycline as a safe and effective treatment for dasatinib-associated acneiform eruption.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-30
Further Info :

Pubmed ID

37868438

DOI: Digital Object Identifier

PMC10590148

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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