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Management of Plaque Psoriasis in Adults: Clinical Utility of Tapinarof Cream.

Author: BhutaniTina, DavisMitchell S, ElhageKareem G, JinJoy Q, LiaoWilson, SpencerRiley K

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Tapinarof, a novel topical aryl hydrocarbon receptor (AHR) agonist, has been approved by the FDA for the treatment of plaque psoriasis. Clinical trials have shown its efficacy, good local tolerability, and a long duration of effect, offering a new non-steroidal option for psoriasis treatment.
Paper Details　
Original Abstract of the Article :
Topical medications represent the most commonly used drugs in the treatment of psoriasis. However, topical steroids are mainly limited to short-term or intermittent use, and traditional non-steroidal topicals such as vitamin D analogues, topical calcineurin inhibitors, and topical retinoids are limi...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613418/

データ提供：米国国立医学図書館（NLM）

Tapinarof Cream: A Novel Topical Treatment for Plaque Psoriasis

This study explores the potential of a novel topical medication, tapinarof cream, for the treatment of plaque psoriasis, a chronic inflammatory skin condition characterized by itchy, scaly patches. Tapinarof, a selective aryl hydrocarbon receptor (AHR) agonist, offers a promising new approach to psoriasis treatment, potentially offering a more effective and well-tolerated alternative to existing therapies.

Tapinarof: A New Tool in the Psoriasis Treatment Arsenal

The study highlights the efficacy and safety of tapinarof in achieving clear skin in adults with moderate-to-severe plaque psoriasis. This medication works by modulating the immune system and reducing inflammation, ultimately leading to improved skin clarity. The study findings suggest that tapinarof could become a valuable addition to the existing psoriasis treatment toolbox, offering a new and effective non-steroidal option for both initial clearance and long-term maintenance of the disease.

Hope for Improved Psoriasis Management

This research offers hope for individuals with plaque psoriasis by highlighting the potential benefits of tapinarof cream. The study findings, like a refreshing oasis in the desert of psoriasis, demonstrate the efficacy and safety of this novel treatment, potentially leading to improved skin health and quality of life for patients.

Dr. Camel's Conclusion

This research, like a camel caravan carrying a precious cargo of hope for psoriasis patients, reveals the promising potential of tapinarof cream. The study findings, like a cool spring in a parched desert, offer a glimmer of hope for more effective and well-tolerated treatment options, leading towards a brighter future for those living with this chronic skin condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-01
Further Info :

Pubmed ID

37905185

DOI: Digital Object Identifier

PMC10613418

Related Literature

Article Analysis
・Effects of tapinarof topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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