Paper Details 
Original Abstract of the Article :
Type 1 diabetes mellitus (T1DM) with obesity is increasingly common, prompting effective clinical interventions to induce weight loss in this population. We present 3 patients with T1DM and obesity prescribed a glucagon-like peptide 1 receptor agonist (GLP-1RA) and pramlintide. <b>Case 1:</b> A 32-y...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580416/

データ提供:米国国立医学図書館(NLM)

GLP-1 Receptor Agonist and Amylin Analogue: A Novel Approach to Obesity in Type 1 Diabetes

The prevalence of obesity, particularly in individuals with type 1 diabetes, is a growing public health concern. This research explores the potential of a combination therapy involving a glucagon-like peptide 1 receptor agonist (GLP-1RA) and pramlintide, an amylin analogue, as a treatment for obesity in individuals with type 1 diabetes. The study presents three case studies of patients with type 1 diabetes and obesity who were prescribed this combination therapy, highlighting its potential benefits in weight loss and glycemic control.

A Promising Combination: GLP-1RA and Pramlintide for Obesity

The case studies demonstrate that the combination therapy of GLP-1RA and pramlintide was associated with significant weight loss in all three patients. The study also observed that pramlintide reduced insulin requirements in all patients while maintaining or improving glycemic control. These findings suggest that this combination therapy may offer a valuable treatment option for individuals with type 1 diabetes and obesity, potentially improving both weight management and glycemic control.

Obesity and Type 1 Diabetes: A Complex Challenge

This research highlights the complexity of managing obesity in individuals with type 1 diabetes, emphasizing the need for innovative and effective treatment strategies. The combination therapy of GLP-1RA and pramlintide offers a promising approach to addressing this challenging condition, potentially improving weight loss, glycemic control, and overall health outcomes. It's like finding a new source of water in a parched desert, providing a lifeline for those struggling with obesity and type 1 diabetes.

Dr.Camel's Conclusion

This study offers a glimmer of hope for individuals with type 1 diabetes and obesity, demonstrating the potential of a combination therapy involving GLP-1RA and pramlintide to achieve significant weight loss and improve glycemic control. The study underscores the ongoing need for research into effective treatment strategies for obesity in this challenging population. It's like discovering a hidden oasis in the vast desert of obesity and type 1 diabetes, offering a source of hope, healing, and a path towards a healthier future.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-02
Further Info :

Pubmed ID

37908483

DOI: Digital Object Identifier

PMC10580416

Related Literature

SNS
PICO Info
in preparation
Languages

English

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