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Efficacy, safety, and dose-response effects of calcifediol supplementation on 25-hydroxyvitamin D, parathyroid hormone, and 1,25-dihydroxyvitamin D levels in healthy adults: An open-label, interventional pilot study.
Author: BhadadaSanjay Kumar, DasLiza, DuttaPinaki, HolickMichael F, MarwahaRaman Kumar, SachdevaNaresh, SinghmarShallu, ThakurNeetika
Original Abstract of the Article :
Vitamin D deficiency (VDD) is highly prevalent across the globe. Cholecalciferol (Vitamin D3) fails to attain sufficient serum concentrations of 25-hydroxyvitamin D (25(OH)D) in a significant proportion of supplemented individuals. Calcifediol (25-hydroxyvitamin D3) is less studied in healthy adults...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.4103/ijp.ijp_873_22
データ提供:米国国立医学図書館(NLM)
Calcifediol: A Promising Option for Vitamin D Supplementation
Maintaining adequate vitamin D levels is crucial for overall health, much like a desert oasis providing essential water for a thriving ecosystem. This research, published in [Journal Name], investigates the efficacy and safety of calcifediol supplementation in healthy adults.
The researchers conducted an open-label, interventional pilot study to assess the effects of calcifediol supplementation on serum levels of 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), and 1,25-dihydroxyvitamin D (1,25(OH)2D). They found that calcifediol supplementation was effective in increasing serum 25(OH)D levels, with minimal effects on PTH and 1,25(OH)2D levels. This suggests that calcifediol could be a promising option for vitamin D supplementation, especially in individuals who have difficulty achieving sufficient levels with cholecalciferol (vitamin D3).
Calcifediol: A New Oasis in Vitamin D Supplementation
This study reveals the potential benefits of calcifediol as a vitamin D supplement. Think of it as discovering a new, refreshing oasis in the vast desert of vitamin D supplementation. Calcifediol's efficacy and safety profile make it a promising alternative for individuals seeking to optimize their vitamin D levels.
Maintaining Vitamin D Levels: A Journey of Health
Adequate vitamin D levels are essential for bone health, immune function, and overall well-being. Think of it as a camel caravan navigating a desert, relying on its essential resources for a successful journey. Consult your doctor for personalized recommendations on vitamin D supplementation and other strategies to maintain optimal levels.
Dr. Camel's Conclusion
This pilot study provides promising evidence for the use of calcifediol as a vitamin D supplement. The findings suggest that calcifediol is effective in increasing serum 25(OH)D levels, offering a potential solution for individuals struggling to achieve adequate vitamin D levels with other forms of supplementation. Remember, maintaining optimal vitamin D levels is crucial for overall health, much like a camel caravan relying on its essential resources for a successful journey across the desert. Consult your doctor for personalized recommendations and explore the possibilities for a healthier future.
Date :
- Date Completed 2023-11-24
- Date Revised 2023-11-24
Further Info :
Related Literature
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