Efficacy, safety, and dose-response effects of calcifediol supplementation on 25-hydroxyvitamin D, parathyroid hormone, and 1,25-dihydroxyvitamin D levels in healthy adults: An open-label, interventional pilot study.

Author: BhadadaSanjay Kumar, DasLiza, DuttaPinaki, HolickMichael F, MarwahaRaman Kumar, SachdevaNaresh, SinghmarShallu, ThakurNeetika

Paper Details 
Original Abstract of the Article :
Vitamin D deficiency (VDD) is highly prevalent across the globe. Cholecalciferol (Vitamin D3) fails to attain sufficient serum concentrations of 25-hydroxyvitamin D (25(OH)D) in a significant proportion of supplemented individuals. Calcifediol (25-hydroxyvitamin D3) is less studied in healthy adults...See full text at original site
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引用元:
https://doi.org/10.4103/ijp.ijp_873_22

データ提供:米国国立医学図書館(NLM)

Calcifediol: A Promising Option for Vitamin D Supplementation

Maintaining adequate vitamin D levels is crucial for overall health, much like a desert oasis providing essential water for a thriving ecosystem. This research, published in [Journal Name], investigates the efficacy and safety of calcifediol supplementation in healthy adults.

The researchers conducted an open-label, interventional pilot study to assess the effects of calcifediol supplementation on serum levels of 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), and 1,25-dihydroxyvitamin D (1,25(OH)2D). They found that calcifediol supplementation was effective in increasing serum 25(OH)D levels, with minimal effects on PTH and 1,25(OH)2D levels. This suggests that calcifediol could be a promising option for vitamin D supplementation, especially in individuals who have difficulty achieving sufficient levels with cholecalciferol (vitamin D3).

Calcifediol: A New Oasis in Vitamin D Supplementation

This study reveals the potential benefits of calcifediol as a vitamin D supplement. Think of it as discovering a new, refreshing oasis in the vast desert of vitamin D supplementation. Calcifediol's efficacy and safety profile make it a promising alternative for individuals seeking to optimize their vitamin D levels.

Maintaining Vitamin D Levels: A Journey of Health

Adequate vitamin D levels are essential for bone health, immune function, and overall well-being. Think of it as a camel caravan navigating a desert, relying on its essential resources for a successful journey. Consult your doctor for personalized recommendations on vitamin D supplementation and other strategies to maintain optimal levels.

Dr. Camel's Conclusion

This pilot study provides promising evidence for the use of calcifediol as a vitamin D supplement. The findings suggest that calcifediol is effective in increasing serum 25(OH)D levels, offering a potential solution for individuals struggling to achieve adequate vitamin D levels with other forms of supplementation. Remember, maintaining optimal vitamin D levels is crucial for overall health, much like a camel caravan relying on its essential resources for a successful journey across the desert. Consult your doctor for personalized recommendations and explore the possibilities for a healthier future.

Date :
  1. Date Completed 2023-11-24
  2. Date Revised 2023-11-24
Further Info :

Pubmed ID

37929406

DOI: Digital Object Identifier

10.4103/ijp.ijp_873_22

SNS
PICO Info
in preparation
Languages

English

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