Early use of intravitreal triamcinolone to inhibit traumatic proliferative vitreoretinopathy: a randomised clinical trial.

Author: ChenSong, GuoHaixia, HeTiangeng, LiuYuanyuan, MengYu, SunZhiyong, SunZhuoyu, YanHua, YangLikun, YangWenhui, YangXueli, YaoBaoqun, YuJinguo, ZhangJingkai, ZhangMingxue

Paper Details 
Original Abstract of the Article :
AIMS: To evaluate the efficacy and safety of intravitreal triamcinolone acetonide (TA) injection at the end of emergency surgery for open globe injury (OGI) to suppress traumatic proliferative vitreoretinopathy (TPVR). METHODS: A single-centre, participant-masked, prospective, randomised controlled...See full text at original site
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引用元:
https://doi.org/10.1136/bjo-2023-324318

データ提供:米国国立医学図書館(NLM)

Triamcinolone Injection: A New Oasis for Traumatic Proliferative Vitreoretinopathy?

Open globe injuries (OGI) are serious eye injuries, like a severe sandstorm that can cause significant damage. This study investigates the potential benefits of using intravitreal triamcinolone acetonide (TA) injection to prevent traumatic proliferative vitreoretinopathy (TPVR), a serious complication of OGI that can lead to vision loss.

Early Intervention: A Strategic Approach to Combatting TPVR

The authors conducted a randomized clinical trial comparing the effectiveness of early TA injection with a control group. The results were promising, indicating that early injection of TA was associated with a significant reduction in TPVR severity. This is a key finding, as it suggests that early intervention with TA may be a valuable tool in mitigating the damaging effects of TPVR.

Improving Surgical Success and Visual Prognosis

In addition to reduced TPVR, the study also found that TA injection was associated with improved final visual acuity and higher retinal attachment rates compared to the control group. These findings are particularly encouraging, as they suggest that early TA intervention may not only prevent TPVR but also lead to better surgical outcomes and improved vision for patients with OGI.

Dr. Camel's Conclusion

This research offers a glimmer of hope in the desert of OGI treatment. Early intravitreal TA injection shows promise as a valuable tool for preventing TPVR, improving surgical outcomes, and potentially preserving vision for those who have suffered OGI. This finding could significantly impact the lives of individuals who have experienced this debilitating injury.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-02
Further Info :

Pubmed ID

38041678

DOI: Digital Object Identifier

10.1136/bjo-2023-324318

Related Literature

SNS
PICO Info
in preparation
Languages

English

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