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Misperceptions and management of LDL-cholesterol in secondary prevention of patients with familial hypercholesterolemia in cardiology practice: Real-life evidence from the EPHESUS registry.

Author: AkayKadriye Halli, AksanGökhan, AktaşMüjdat, AşkınLütfü, BaşaranÖzcan, BekarLütfü, BitekerMurat, CinierGöksel, DemirVahit, DemirelliSelami, DervişEmir, DoğanVolkan, GencerErkan, KalçıkMacit, KaradenizFatma Özpamuk, KayıkciogluMeral, MertGurbet Özge, MertKadir Uğur, PekelNihat, Rencüzoğullarıİbrahim, ResulzadeMübariz Murat, TekinalpMehmet, Utku Şenol, ÇelikOğuzhan, ÇilCem, Özdemirİbrahim Halil, ÖzlekBülent, ÖzlekEda, İnciSinan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the management of familial hypercholesterolemia (FH) patients with atherosclerotic cardiovascular disease (ASCVD) in cardiology practice, highlighting the importance of achieving LDL-C goals to prevent complications of this inherited disease.
Paper Details　
Original Abstract of the Article :
Familial hypercholesterolemia (FH) is a common inherited disease, leading to premature atherosclerotic cardiovascular disease (ASCVD) due to elevated low-density lipoprotein cholesterol (LDL-C) levels. Achieving LDL-C goals is extremely important for preventing the complications of this fatal diseas...See full text at original site
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引用元：
https://doi.org/10.1016/j.jacl.2023.09.013

データ提供：米国国立医学図書館（NLM）

Familial Hypercholesterolemia: A Challenging Lipid Landscape

Familial hypercholesterolemia (FH) is a genetic disorder that causes high levels of low-density lipoprotein cholesterol (LDL-C), increasing the risk of premature cardiovascular disease. This research investigates the management of FH patients with cardiovascular disease in a real-world setting.

LDL-C Management: A Crucial Step in Preventing Cardiovascular Disease

The researchers found that LDL-C management in FH patients with cardiovascular disease often falls short of recommended guidelines. This suggests a need for improved awareness and adherence to evidence-based treatment protocols to minimize the risk of cardiovascular complications in these patients.

Navigating the Lipid Landscape: Taking Control of Cholesterol

This research underscores the importance of early diagnosis and aggressive LDL-C management in individuals with FH. Just as a camel adapts to the arid desert environment to survive, FH patients need to proactively manage their cholesterol levels to reduce their risk of cardiovascular disease. This research provides valuable insights into the challenges and opportunities for optimizing care in this patient population.

Dr. Camel's Conclusion

FH, like a hidden desert oasis, requires a specific approach to ensure survival. This research highlights the need for enhanced LDL-C management strategies to navigate the challenging lipid landscape of FH and protect patients from the devastating consequences of this inherited disorder.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-10
Further Info :

Pubmed ID

38072583

DOI: Digital Object Identifier

10.1016/j.jacl.2023.09.013

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English

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