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Early serum sodium changes in elderly patients with nocturia receiving desmopressin.

Author: AbuelnagaMohamed, MostafaDiaaeldin, MouradSherif, SatourAshraf

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Desmopressin effectively reduced nocturia symptoms in elderly patients, but it was associated with a statistically significant sodium drop in females. To minimize hyponatremia risk, the minimal effective dose should be used, and baseline sodium levels must be ≥135 mmol/L. Close monitoring of sodium levels is recommended at 7, 14, and 30 days after treatment initiation, especially for high-risk patients and those taking other hyponatremia-inducing medications.
Paper Details　
Original Abstract of the Article :
PURPOSE: The purpose of the study is to identify early serum sodium changes that could happen in elderly patients with nocturia receiving desmopressin. MATERIALS AND METHODS: This study was conducted on 28 patients complaining of nocturia and receiving desmopressin. Inclusion criteria were patients...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10699174/

データ提供：米国国立医学図書館（NLM）

Early Serum Sodium Changes in Elderly Patients Receiving Desmopressin

Nocturia, frequent urination at night, is a common issue, especially among the elderly. This research investigates the early serum sodium changes that can occur in elderly patients with nocturia receiving desmopressin, a medication used to reduce urine production. The study analyzes the serum sodium levels of elderly patients with nocturia after initiating desmopressin treatment. The findings reveal a significant decrease in nocturnal urine volume and a delay in time to the first void, but also highlight a potential for sodium drops in some patients, particularly females. The study underscores the importance of close monitoring for sodium levels, especially in elderly patients, to minimize the risk of hyponatremia.

Desmopressin: A Potential for Sodium Changes in Elderly Patients

The study's findings highlight the importance of monitoring serum sodium levels in elderly patients receiving desmopressin for nocturia. While desmopressin effectively reduced nocturnal urine volume and improved nighttime voiding frequency, it also showed a potential for sodium drops in some patients, particularly females. These findings emphasize the need for vigilant monitoring of sodium levels, especially in high-risk patients, to ensure safe and effective treatment with desmopressin.

A Camel's Perspective on Nocturia Treatment

Nocturia can disrupt sleep and affect quality of life, much like a camel encountering a mirage in the desert, a false promise of relief. This research explores the use of desmopressin for nocturia, highlighting the potential for sodium changes, particularly in elderly patients. The study's findings underscore the importance of careful monitoring, ensuring that treatment is effective and safe, just as a camel navigates the desert with caution and vigilance.

Dr.Camel's Conclusion

This study underscores the importance of careful monitoring of serum sodium levels in elderly patients receiving desmopressin for nocturia. While desmopressin can effectively reduce nocturnal urine volume, it also has the potential to cause sodium drops in some patients. Therefore, regular sodium monitoring is crucial for ensuring safe and effective treatment with desmopressin.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-11
Further Info :

Pubmed ID

38074185

DOI: Digital Object Identifier

PMC10699174

Related Literature

Article Analysis
・Side Effects of desmopressin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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