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The mutagenic activity of anti-cancer drugs and the urine of rats given these drugs.
Author: IwasakiT, MiyakawaM, PakK, YoshidaO
Original Abstract of the Article :
Twenty-one anti-cancer drugs have been tested for their ability to cause mutations in Salmonella typhimurium test strains in the Salmonella/microsome mutagenicity test. Nine of the 21 anticancer drugs showed this ability: cyclophosphmide, nitromin, thio-tepa, busulfan, 6-mercaptopurine, neocarzinost...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/BF00254692
データ提供:米国国立医学図書館(NLM)
Anticancer Drugs: Exploring their Mutagenic Potential
This study investigates the mutagenic activity of various anticancer drugs using the Salmonella/microsome mutagenicity test. The researchers tested 21 drugs for their ability to cause mutations in Salmonella typhimurium strains. They also investigated the mutagenic potential of urine from rats treated with these drugs.
Anticancer Drugs' Mutagenic Activity: A Double-Edged Sword
The study found that nine out of the 21 anticancer drugs tested exhibited mutagenic activity. The urine from rats treated with six of these drugs also showed mutagenic properties, highlighting the potential for these drugs to induce genetic changes.
Anticancer Therapy: A Balancing Act Between Benefits and Risks
This research provides valuable insights into the potential mutagenic effects of anticancer drugs. It emphasizes the importance of considering both the therapeutic benefits and potential risks of these drugs.
Dr. Camel's Conclusion
Just like a camel navigates a treacherous desert, anticancer drugs can be powerful tools for fighting cancer, but they also carry potential risks. This study reminds us that even while seeking a cure, we must be aware of the potential side effects and strive to find the most effective and safest treatment options.
Date :
- Date Completed 1979-10-24
- Date Revised 2019-09-11
Further Info :
Related Literature
English
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