[Fundamental and clinical studies on aztreonam in obstetrics and gynecology].

Author: HagaH, IshikawaM, MizoguchiH, MureK, SakurabaM, ShimizuT, ToriiY, YamashitaK, YamazakiT, YorozuY

Paper Details 
Original Abstract of the Article :
Aztreonam (AZT), a monobactam antibiotic, is known to have a high activity against Gram-negative bacteria. Fundamental and clinical studies were carried out on AZT with the following results. Following 1 g of bolus intravenous injection, the transfer of AZT to uterine artery and internal genital org...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3834133

データ提供:米国国立医学図書館(NLM)

Aztreonam: A Monobactam Antibiotic Showing Promise in Obstetrics and Gynecology

The world of antibiotics is a vast and complex desert, where researchers tirelessly seek new ways to fight off infections. This study focuses on a particular antibiotic called aztreonam (AZT), a monobactam antibiotic known for its potent action against gram-negative bacteria. It delves into the potential of AZT in the realm of obstetrics and gynecology, exploring its fundamental properties and clinical efficacy in this field.

The researchers aimed to investigate the distribution of AZT within the body after intravenous administration, specifically focusing on its transfer to the uterine artery and internal genital organs. They found that after a 1-gram bolus injection, AZT achieved satisfactory levels in both the uterine artery and internal genital organs. This finding is akin to a well-placed oasis in the desert, providing evidence of the drug's ability to reach targeted areas in the body.

Aztreonam: A Promising Treatment for Obstetrics and Gynecology Infections

The study also evaluated the clinical effectiveness of AZT in treating infections in pregnant women. They reported an impressive overall efficacy rate of 94.4%, with excellent results in 4 cases and good results in 13 cases. This data paints a promising picture for AZT's potential as a safe and effective treatment option for various infections encountered in obstetrics and gynecology.

Protecting Mothers and Babies: Navigating the Desert of Infection

This research offers a beacon of hope for treating infections in pregnant women, a particularly vulnerable group. It underscores the importance of exploring and developing new antibiotic options that are safe and effective for this population. Remember, just like a desert traveler must be prepared for the unpredictable, healthcare professionals must be ready to tackle the ever-evolving challenges of infectious diseases.

Dr. Camel's Conclusion

This study unveils the potential of aztreonam in obstetrics and gynecology, showing its ability to reach targeted areas in the body and offering encouraging results in treating infections. This research serves as a reminder that exploration and innovation remain crucial in the field of infectious diseases, as we constantly strive to find new ways to fight off infection and protect the most vulnerable among us.

Date :
  1. Date Completed 1986-05-23
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3834133

DOI: Digital Object Identifier

3834133

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PICO Info
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Languages

Japanese

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