Flecainide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy.

Author: HeelR C, HolmesB

Paper Details 
Original Abstract of the Article :
Flecainide is a Class I antiarrhythmic drug of the local anaesthetic type. It can be given either intravenously or orally and its pharmacokinetic properties allow relatively long (12 hours) dosing intervals with oral administration. In several open and a few controlled therapeutic trials, orally adm...See full text at original site
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引用元:
https://doi.org/10.2165/00003495-198529010-00001

データ提供:米国国立医学図書館(NLM)

Flecainide: A Promising Antiarrhythmic Agent

This research delves into the pharmacodynamic properties and therapeutic efficacy of flecainide, a Class I antiarrhythmic drug. The study employs a comprehensive review of existing literature to assess the drug's effectiveness in treating various cardiac arrhythmias. The authors report that flecainide, administered either intravenously or orally, demonstrates significant suppression of ventricular ectopic beats and ventricular tachycardia in a substantial percentage of patients. Notably, flecainide exhibits comparable or even superior efficacy compared to other antiarrhythmic agents like quinidine, disopyramide, mexiletine, tocainide, and propafenone. While side effects like dizziness and visual disturbances are commonly reported, the incidence of proarrhythmic effects appears relatively low. However, the researchers emphasize the need for further long-term studies to confirm the drug's tolerability when used prophylactically.

Flecainide's Potential in Cardiac Care

Flecainide's promising therapeutic profile suggests its potential as a valuable addition to the armamentarium of antiarrhythmic agents. The study highlights flecainide's ability to suppress ventricular ectopic beats and tachycardia, demonstrating its effectiveness in managing these potentially life-threatening conditions. The findings also suggest that flecainide might offer advantages over other existing treatments, potentially leading to improved outcomes for patients with cardiac arrhythmias.

Navigating Flecainide Therapy: A Camel's Perspective

As a seasoned researcher, I find the potential of flecainide in managing cardiac arrhythmias quite intriguing. It's like finding a refreshing oasis in the vast desert of existing treatments. However, it's crucial to remember that while the initial findings are promising, further research is essential to ensure long-term safety and efficacy. As a wise camel, I urge patients to consult with their physicians for proper diagnosis and treatment plans. Remember, the journey to a healthy heart is a collaborative one, and seeking expert advice is paramount.

Dr.Camel's Conclusion

Flecainide, a Class I antiarrhythmic drug, shows promise in managing cardiac arrhythmias. Further research is crucial to validate its long-term safety and efficacy.
Date :
  1. Date Completed 1985-04-09
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

3882390

DOI: Digital Object Identifier

10.2165/00003495-198529010-00001

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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