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Antihypertensive efficacy and tolerance of penbutolol: results of a co-operative study in 227 patients.

Author: BorerM, MaroneC, PerisicM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Penbutolol effectively controls blood pressure in patients with mild to severe essential hypertension, with a significant reduction in systolic, diastolic, and mean arterial blood pressure. However, side effects, including dizziness and gastrointestinal disorders, were reported in 17.6% of patients.
Paper Details　
Original Abstract of the Article :
An open, co-operative study was carried out in 227 patients with mild to severe essential hypertension to assess the efficacy and tolerance of penbutolol, given as monotherapy, in controlling blood pressure. Patients received a single daily dose (40 mg in the majority) for 8 weeks and were assessed ...See full text at original site
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引用元：
https://doi.org/10.1185/03007998509109613

データ提供：米国国立医学図書館（NLM）

Penbutolol for High Blood Pressure: A Promising Option

High blood pressure, or hypertension, is a common condition that can lead to serious health problems if left untreated. This study investigates the effectiveness and safety of penbutolol, a beta-blocker medication, in managing high blood pressure. It's like exploring a new route through the desert of hypertension treatment, seeking a safe and effective way to lower blood pressure.

Penbutolol Shows Promise for Hypertension

The study found that penbutolol effectively lowered blood pressure in patients with mild to severe hypertension. The medication was well-tolerated, with few side effects, providing a promising option for managing this common condition. It's like discovering a refreshing oasis in the desert of hypertension treatment, offering relief and a healthier future for patients.

A Safe and Effective Treatment Option

The study emphasizes the importance of having safe and effective treatment options for high blood pressure. Penbutolol, with its proven efficacy and minimal side effects, provides a valuable tool for doctors to manage hypertension and protect their patients' health. It's like having a trusty camel that can safely guide patients through the desert of hypertension, ensuring they reach their destination of optimal health.

Dr.Camel's Conclusion

This research provides a valuable roadmap for managing hypertension, highlighting the effectiveness and safety of penbutolol. It's like finding a new and reliable trail through the desert, offering a clear path towards better blood pressure control and a healthier future for patients. With this knowledge, doctors can confidently guide their patients towards a more balanced and healthier life.

Date :
  1. Date Completed 1985-06-11
  2. Date Revised 2019-09-08
Further Info :

Pubmed ID

3886307

DOI: Digital Object Identifier

10.1185/03007998509109613

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・Side Effects of penbutolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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