[Clinical trials of BRL 25000 (clavulanic acid-amoxicillin) granules on skin and soft tissue infections in the field of pediatrics].

Author: HaradaM, IrikiT, IshimotoK, KogaT, MotohiroT, NishiyamaT, ShimadaY, TanakaK, TominagaK, TomitaN

Paper Details 
Original Abstract of the Article :
BRL 25000 is a combination of a newly-developed beta-lactamase inhibitor clavulanic acid (CVA) and amoxicillin (AMPC) in the ratio of 1 to 2. The drug, as medium granules, was administered to a total of 92 pediatric patients, ranging in age from 1 month to 13 years and 2 months, with cutaneous/soft ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3892077

データ提供:米国国立医学図書館(NLM)

BRL 25000: A Promising Combination Therapy for Skin Infections

The [treatment of skin and soft tissue infections] in children is a crucial area of [pediatric medicine]. This research investigates the efficacy and safety of [BRL 25000], a combination of [clavulanic acid (CVA)] and [amoxicillin (AMPC)], in treating [cutaneous/soft tissue infections] in children. The authors conducted a [clinical trial] involving 92 pediatric patients to evaluate the [clinical efficacy, bacteriological effects, and side effects] of this new drug.

Effective Treatment with Minimal Side Effects: A Safe and Powerful Option

The study found that [BRL 25000] was effective in treating a variety of [skin and soft tissue infections] in children, including [impetigo], [furuncle], [phlegmon], [abscess], and [lymphadenitis]. The authors observed a [high rate of clinical cure] with [minimal side effects]. Furthermore, [BRL 25000] demonstrated [potent antibacterial activity] against [S. aureus], a common pathogen associated with these infections.

Implications for Pediatric Infectious Disease Management

This research highlights the potential of [BRL 25000] as a safe and effective treatment for [skin and soft tissue infections] in children. The combination of [CVA] and [AMPC] provides a [broader spectrum of antibacterial activity] and [overcomes resistance] to [beta-lactamase-producing bacteria], making it a valuable therapeutic option for [pediatric infectious disease management].

Dr. Camel's Conclusion

This research is a testament to the ingenuity of medical professionals in developing new and effective treatments for common childhood ailments. Like a camel traversing the desert, researchers have found a valuable new tool in the fight against skin infections, offering hope for a healthier future for children.

Date :
  1. Date Completed 1985-07-30
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3892077

DOI: Digital Object Identifier

3892077

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PICO Info
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Languages

Japanese

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