Side Effects of cephalexin: A Synthesis of Findings from 27 Studies

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This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Side Effects of cephalexin: A Synthesis of Findings from 27 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

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This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Major research findings

Studies evaluating the effectiveness and safety of cephalexin have shown its efficacy against a range of infections. For example, the effectiveness of cephalexin against skin and skin structure infections has been shown to be comparable to azithromycin given as a once-daily regimen over five days. 16 Cephalexin has also been demonstrated to be effective against various infections, including ear, nose, and throat infections, pediatric infections, urinary tract infections, skin and soft tissue infections, respiratory infections, and chronic bronchitis. 9 25 26 4 3 15 18 19 14 27 23 17 5 12 24 2 13 7 22 1 8 11 21 6 20 10

Reasons for side effects

Side effects of cephalexin are mainly caused by the process of drug absorption and metabolism in the body. It is thought that some components affect the body when the drug is broken down in the body. 9

Common side effects

Gastrointestinal

The most common side effects of cephalexin are gastrointestinal symptoms. Diarrhea, soft stools, abdominal pain, nausea, and vomiting have been reported. 16 25 15 18 17 5 12 24 2 13 11 6 7 14 10

Allergic reactions

Rarely, allergic reactions to cephalexin may occur. If symptoms such as rash, itching, hives, or difficulty breathing appear, consult a doctor immediately. 16 10

Liver dysfunction

Cephalexin can rarely cause liver dysfunction. Symptoms of liver dysfunction include jaundice (yellowing of the skin and whites of the eyes), dark urine, loss of appetite, nausea, and fatigue. Consult a doctor immediately if you experience these symptoms. 25

Blood disorders

Cephalexin can rarely cause blood disorders. Symptoms of blood disorders include fever, fatigue, easy bleeding, and easy bruising. Consult a doctor immediately if you experience these symptoms. 25

Side effects countermeasures

Gastrointestinal

If you are concerned about gastrointestinal symptoms, eat small meals more frequently. It is also important to stay hydrated. Consult a doctor if symptoms do not improve. 16 12

Allergic reactions

If you have an allergic reaction, consult a doctor immediately. Antihistamines or steroids may be prescribed if necessary. 16 10

Liver dysfunction

If you have symptoms of liver dysfunction, consult a doctor immediately. Liver function tests will be performed, and treatment will be provided if necessary. 25

Blood disorders

If you have symptoms of blood disorders, consult a doctor immediately. Blood tests will be performed, and treatment will be provided if necessary. 25

Comparison between studies

Commonalities

Many studies have shown that cephalexin is effective against a variety of infections. There is a common understanding that cephalexin is a relatively safe drug with few side effects.

Differences

There are some differences in the effectiveness and side effects of cephalexin depending on the study. This is likely due to differences in research methods and subjects. For example, the dosage and duration of cephalexin, the age and symptoms of the subjects, and concomitant medications can all affect the effectiveness and side effects.

Precautions for real-life applications

It is important to take cephalexin as directed by your doctor. Do not take it or stop taking it without consulting your doctor. If you experience any abnormalities while taking cephalexin, consult a doctor immediately.

Limitations of current research

Research on the effectiveness and side effects of cephalexin is not yet sufficient. In particular, further research is needed on the effects of long-term use and the effectiveness and side effects in specific patient groups.

Future research directions

Further research is needed on the effects of long-term use of cephalexin and the effectiveness and side effects in specific patient groups. Ongoing monitoring of the emergence of cephalexin-resistant bacteria is also necessary.

Conclusion

Cephalexin is a drug effective against a variety of infections. However, there is a possibility of side effects. Take cephalexin as directed by your doctor and consult your doctor immediately if you experience any abnormalities while taking it.

Keywords
Benefit Keywords
Antibacterial effect
Effective against skin infections
Effective for skin and soft tissue infections
Effective for skin infections
Effective skin and soft tissue infections treatment
Effective skin infection treatment
Effective skin infections
Low side effects
S6472 effective for skin infections
S6472 effectiveness
S6472 safe
S6472 safety
Safe
Safe and useful
Safe for patients
Safe for skin infection treatment
Skin and soft tissue infection treatment
Skin infection treatment
Useful
Useful for skin infection treatment
1
UTI treatment
2
Good clinical evaluation
3
Cephemic cofosfolactamine effective
Cephemic cofosfolactamine effectiveness
Cephemic cofosfolactamine safety
Effective against systemic infections
Effective for systemic infections
Effective systemic infection treatment
Effective systemic infections
Effective systemic infections treatment
Higher recovery rates
Infection treatment
Low side effects
Lower side effects
Systemic infection treatment
4
Bronchitis treatment
COLD treatment
Cephalexin-bromhexine effectiveness
Cephalexin/bromhexine effective for bronchitis
Chronic bronchitis treatment
Chronic obstructive bronchitis treatment
Chronic obstructive pulmonary disease treatment
Effective against bronchitis
Effective bronchitis treatment
Effective chronic bronchitis
Effective chronic obstructive bronchitis treatment
Effective for chronic bronchitis
Reduced mucus buildup
5
Effective otitis media treatment
6
Antibacterial effect
Bacterial bronchitis treatment
Bronchitis treatment
Effective against bacterial bronchitis
Effective bacterial bronchitis
Effective bacterial bronchitis treatment
Effective bronchitis treatment
Effective for bacterial bronchitis
Low incidence of side effects
Low side effects
S6472 effective for bacterial bronchitis
S6472 effectiveness
S6472 safe
S6472 safety
Safe and useful
Safe for patients
7
Cefaclor effective for UTIs
Cefaclor effectiveness
Cefaclor efficacy
Cefaclor safe
Effective UTI treatment
Effective against UTI
Effective for urinary tract infections
Effective urinary tract infections
Effective urinary tract infections treatment
Low side effects
Safe and useful
Safe for patients
Safe for urinary tract infections
Trimethoprim-sulfamethoxazole effectiveness
Urinary tract infection treatment
Urinary tract treatment
8
Antibiotic effectiveness
Antibiotic efficacy
Cephalosporin blood levels
Effective treatment for H. pylori infection
HPLC analysis
Improved HPLC method for cefradine analysis
Improved cephalosporin dosage
9
Accurate allergy diagnosis
10
Febrile diseases treatment
Respiratory tract infection treatment
11
Amoxicillin-clavulanic acid effectiveness
Cefaclor effective for soft tissue infections
Cefaclor effectiveness
Effective against soft tissue infections
Effective for soft tissue infections
Effective soft tissue infection treatment
Effective soft tissue infections
Effective soft tissue infections treatment
Soft tissue infection treatment
Soft tissue treatment
12
Good cutaneous distribution
Pediatric infections treatment
13
Cefroxadine effective for otitis media
Cefroxadine effectiveness
Cefroxadine safety
Effective acute otitis media treatment
Effective against otitis media
Effective chronic otitis media treatment
Effective for otitis media
Effective otitis media
Effective otitis media treatment
Otitis media treatment
Otitis treatment
Safe
Safe and effective
Safe for otitis media treatment
14
Bacteriologically effective
Effective for skin infections
15
5-day treatment effective
Antibacterial activity
Azithromycin effective
Bacteriological efficacy
Bacteriological eradication
Clinical efficacy
Clinical response
Effective skin infection treatment
Effective treatment
Infection treatment
Skin infection treatment
Well tolerated
16
Antibacterial activity
Antibacterial effect
BRL 25000 effective against S. aureus
BRL 25000 effectiveness
Cutaneous/soft tissue infection treatment
Effective against S. aureus
Effective against infections
Effective against skin infections
Effective cutaneous/soft tissue infections
Effective cutaneous/soft tissue infections treatment
Effective for soft tissue infections
Effective skin infection treatment
Effective skin infections
Potent antibacterial
Potent antibacterial activity
17
Antibacterial effect
Bacterial infection treatment
Effective against bacterial infections
Effective against infections
Effective bacterial infection treatment
Effective bacterial infections
Effective bacterial infections treatment
Effective for bacterial infections
Effective for various infections
Effective mild/moderate infections
Long serum concentration
Low side effects
S 6472 effectiveness
S6472 effective against infections
S6472 safe
Safe for children
18
Antibacterial activity
Ciprofloxacin effective typhoid fever
Ciprofloxacin treatment
Effective treatment
Effective typhoid fever treatment
Effective typhoid treatment
Pain relief
Satisfactory response
Typhoid fever treatment
19
Antibacterial activity
Antibiotic treatment
Bone infection treatment
Cephalexin effective
Effective osteomyelitis treatment
Infection treatment
Inflammation reduction
Inflammation relief
Osteomyelitis treatment
Prevent bacterial spread
Prevent bacterial spreading
Prevented bacterial spreading
Prevention of bacterial spreading
Prevents bacterial spreading
Reduced inflammation
Treatment of chronic osteomyelitis
20
Antibacterial effect
Bronchitis treatment
Chronic bronchitis treatment
Effective against chronic bronchitis
Effective bronchitis treatment
Effective chronic bronchitis
Effective chronic bronchitis treatment
Effective for chronic bronchitis
Low side effects
Low toxicity
S 6472 effectiveness
S6472 effective for chronic bronchitis
Safe for patients
21
Antimicrobial effect
Cefaclor effectiveness
Cefaclor safe for gut flora
Cefaclor safety
Effective antibiotic
Effective for bacterial infections
Effective infection treatment
Low side effects
Microflora normalization
Minimal impact on gut flora
No microbial resistance
Safe
Safe and effective
Safe for oral administration
Safe for patients
22
Cephalexin effective for UTIs
Cephalexin effectiveness
Cephalexin safe
Effective UTI treatment
Effective against UTI
Effective for UTI
Effective for urinary tract infections
Effective lower UTI treatment
Effective lower urinary tract infections
Effective urinary tract infections treatment
Lower urinary tract infection treatment
Safe and effective
Safe for lower urinary tract infections
Short course
Urinary tract infection treatment
Urinary tract treatment
23
Acute otitis media treatment
Amoxicillin-clavulanate effectiveness
Augmentin effective for acute otitis media
Effective acute otitis media treatment
Effective against otitis media
Effective for acute otitis media
Effective otitis media
Effective otitis media treatment
Otitis media treatment
24
Effective otorhinolaryngology treatment
25
Antibacterial activity
Antibacterial efficacy
Antibiotic treatment
Bacteriological efficacy
Cefteram pivoxil effective
Clinical efficacy
Effective pediatric antibiotic
Effective pediatric treatment
Effective treatment
Pediatric infection treatment
Superior antibacterial activity
26
Antimicrobial effect
Cephalexin effective for respiratory infections
Cephalexin effectiveness
Cephalexin safe
Effective against respiratory infections
Effective for respiratory infections
Effective respiratory infection treatment
Effective respiratory infections
Effective respiratory tract infections
Effective respiratory tract infections treatment
Low toxicity
Respiratory tract infection treatment
Respiratory tract treatment
Safe and effective
Safe for respiratory tract infections
27
Risk Keywords
Cefaclor less effective
Gastrointestinal side effects
Mild side effects
Minor side effects
Side effects
1
Minor side effects
2
Similar side effects
3
Cephalexin less effective
Few side effects
Fosfomycin less effective
Lower rate of side effects
Side effects
4
Gastric pyrosis
Gastrointestinal side effects
Nausea
Nausea risk
Pyrosis
Pyrosis risk
5
Side effects
6
Abnormal laboratory findings
Cefaclor less effective
Mild side effects
Minor side effects
Side effects
7
Mild side effects
Minor side effects
Side effects
Trimethoprim-sulfamethoxazole side effects
8
Anaphylactic shock
Anaphylaxis
10
Slight diarrhea
11
Amoxicillin-clavulanic acid side effects
Gastrointestinal issues
Gastrointestinal side effects
12
Cephalexin less effective
Digestive issues
Digestive organ side effects
Digestive organ symptoms
Digestive side effects
14
Abnormal lab values
GI side effects
15
Gastrointestinal disturbance
Gastrointestinal disturbances
Gastrointestinal issues
Gastrointestinal side effects
Treatment withdrawal
16
Gastrointestinal issues
Gastrointestinal side effects
Gastrointestinal upset
Minor side effects
No side effects
17
No significant side effects
18
Chloramphenicol resistance
Drug resistance
Minimal side effects
Minimal side-effects
Side effects
Typhoid fever
Variable response to drugs
19
No serious side effects
Side effects
20
No side effects
No significant side effects
21
Minor changes in microflora
Minor microflora changes
22
Nitrofurantoin less effective
Relapse
23
Abdominal pain
Adverse effects
Augmentin more side effects
Cefaclor less effective
Diaper rash
Gastrointestinal side effects
Loose stools
Severe abdominal pain
Side effects
Stool issues
Vomiting
24
Mild side effects
Transient lab abnormalities
25
Increased platelet count
Side effects
26
Cephalexin ineffective against Haemophilus influenzae
Haemophilus influenzae resistance
Haemophilus resistance
Ineffective against Haemophilus influenzae
Ineffective for H. influenzae
Ineffective for Haemophilus influenzae
May not treat meningitis
Meningitis exclusion
Meningitis risk
Reduced effectiveness for H. influenzae
27
Literature analysis of 27 papers
Positive Content
27
Neutral Content
0
Negative Content
0
Article Type
6
0
0
1
27
1.

[Clinical evaluation of S6472 (prolonged action preparation of cefaclor) in the treatment of skin and soft tissue infections. A double blind comparison of S6472 and cefaclor].

Author: SakaiK, FujimotoM, UedaT, YuraJ, ShinagawaN, IshikawaS, TachiY, KobeA, ShibataY, DoiS

Antibacterial effect
Effective against skin infections
Effective for skin and soft tissue infections
Effective for skin infections
Effective skin and soft tissue infections treatment
Effective skin infection treatment
Effective skin infections
Low side effects
S6472 effective for skin infections
S6472 effectiveness
S6472 safe
S6472 safety
Safe
Safe and useful
Safe for patients
Safe for skin infection treatment
Skin and soft tissue infection treatment
Skin infection treatment
Useful
Useful for skin infection treatment
Cefaclor less effective
Gastrointestinal side effects
Mild side effects
Minor side effects
Side effects

A study compared S6472 and cefaclor for skin and soft tissue infections. Both showed similar efficacy (78.9% vs. 82.5%) and safety (4.1% vs. 1.6% side effects). S6472 given twice a day is as effective as cefaclor given three times a day.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

2.

[Comparative studies of the efficacy, safety and usefulness of S6472, cefaclor and cephalexin on complicated urinary tract infection by the double-blind method].

Author: KamidonoS, ArakawaS, FujiiA, KataokaN, UmezuK, IshigamiJ, HirookaK, ShimataniN, MatsushitaM, HikosakaK

UTI treatment
Minor side effects

Cefaclor (standard and long-acting formulations) and cephalexin were all effective for uncomplicated urinary tract infection in 385 patients. All three had a low rate of side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

3.

[Double-blind comparison of cefadroxil and cephalexin granules in the treatment of impetigo].

Author: ArataJ, NoharaN, SuwakiM, UmemuraS, NakagawaS, MiyoshiK, YamamotoY, NishiharaO, YamadaM, HiramatsuH

Good clinical evaluation
Similar side effects

Cefadroxil was slightly better than cephalexin in treating impetigo in children, but the difference was not statistically significant.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

4.

A multicenter, randomized parallel double-blind study comparing three antibiotics, cephemic-cofosfolactamine, fosfomycin and cephalexin, in the treatment of systemic infections.

Author: ManginiP, CicchettiM, BottaroL, MessinaV, BrancadoroM T, PuppoF

Cephemic cofosfolactamine effective
Cephemic cofosfolactamine effectiveness
Cephemic cofosfolactamine safety
Effective against systemic infections
Effective for systemic infections
Effective systemic infection treatment
Effective systemic infections
Effective systemic infections treatment
Higher recovery rates
Infection treatment
Low side effects
Lower side effects
Systemic infection treatment
Cephalexin less effective
Few side effects
Fosfomycin less effective
Lower rate of side effects
Side effects

A study of 127 hospitalized patients compared three antibiotics for systemic infections. Cephemic cofosfolactamine showed significantly higher recovery rates and fewer side effects compared to cephalexin and fosfomycin.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

6.

[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children].

Author: BabaS, KinoshitaH, MoriY, SuzukiK, ShimadaJ, KawamuraS, OnishiS, UedaR, KobayashiK, ItohY

Effective otitis media treatment
Side effects

Cefixime (CFIX) was as effective as cefaclor (CCL) in treating acute suppurative otitis media in children. CFIX was significantly superior to CCL in eradicating bacteria (97.1% vs 90.3%, P<.05) and improving individual symptoms. Both drugs were well tolerated.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

7.

[A double-blind comparative study on the efficacy of S6472, cefaclor, in the treatment of bacterial bronchitis].

Author: OshimaS, YokoyamaY, KikuiriT, MurakamiT, NishiharaH, ShimizuT, AbeM, KuriharaY, ItohC, TakeuchiK

Antibacterial effect
Bacterial bronchitis treatment
Bronchitis treatment
Effective against bacterial bronchitis
Effective bacterial bronchitis
Effective bacterial bronchitis treatment
Effective bronchitis treatment
Effective for bacterial bronchitis
Low incidence of side effects
Low side effects
S6472 effective for bacterial bronchitis
S6472 effectiveness
S6472 safe
S6472 safety
Safe and useful
Safe for patients
Abnormal laboratory findings
Cefaclor less effective
Mild side effects
Minor side effects
Side effects

S6472 (long-acting cefaclor) was found to be equally effective in treating bacterial bronchitis as cefaclor, with similar safety profiles. It can be taken twice a day instead of three times a day.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

8.

A comparison of cefaclor versus trimethoprim-sulfamethoxazole combination in the treatment of acute urinary infections.

Author: RousS N

Cefaclor effective for UTIs
Cefaclor effectiveness
Cefaclor efficacy
Cefaclor safe
Effective UTI treatment
Effective against UTI
Effective for urinary tract infections
Effective urinary tract infections
Effective urinary tract infections treatment
Low side effects
Safe and useful
Safe for patients
Safe for urinary tract infections
Trimethoprim-sulfamethoxazole effectiveness
Urinary tract infection treatment
Urinary tract treatment
Mild side effects
Minor side effects
Side effects
Trimethoprim-sulfamethoxazole side effects

Cefaclor was as effective as trimethoprim-sulfamethoxazole in treating urinary tract infections in 57 women (100% sterile urine during and after treatment), with no significant side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

10.

Outcomes and safety of drug provocation tests.

Author: AunMarcelo Vivolo, BisaccioniCarla, GarroLaila Sabino, RodriguesAdriana Teixeira, TannoLuciana Kase, EnsinaLuis Felipe Chiaverini, KalilJorge, MottaAntônio Abílio, Giavina-BianchiPedro

Accurate allergy diagnosis
Anaphylactic shock
Anaphylaxis

Drug provocation tests (DPTs) are a safe and reliable method for diagnosing drug allergies when performed under the supervision of an allergist. The study found that DPTs are generally safe, but two severe reactions (anaphylaxis) were observed.

Evaluation StudyResearch that systematically evaluates the effectiveness of a particular program or policy. It measures its outcomes and provides important information for future decision-making.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

12.

Double-blind comparative study of two dosage regimens of cefaclor and amoxicillin-clavulanic acid in the outpatient treatment of soft tissue infections.

Author: PienF D

Amoxicillin-clavulanic acid effectiveness
Cefaclor effective for soft tissue infections
Cefaclor effectiveness
Effective against soft tissue infections
Effective for soft tissue infections
Effective soft tissue infection treatment
Effective soft tissue infections
Effective soft tissue infections treatment
Soft tissue infection treatment
Soft tissue treatment
Amoxicillin-clavulanic acid side effects
Gastrointestinal issues
Gastrointestinal side effects

Cefaclor and amoxicillin-clavulanic acid were both effective in treating soft tissue infections (cure rates 64%–85%), but amoxicillin-clavulanic acid caused more gastrointestinal issues.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

14.

[Double-blind comparative trial of cefroxadine and cephalexin in the treatment of acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media].

Author: BabaS, MuraiK, KinoshitaH, KawaiT, KoyamaK, TsukiyamaM, MaruoT, WadaK, InagakiM, MatsushitaT

Cefroxadine effective for otitis media
Cefroxadine effectiveness
Cefroxadine safety
Effective acute otitis media treatment
Effective against otitis media
Effective chronic otitis media treatment
Effective for otitis media
Effective otitis media
Effective otitis media treatment
Otitis media treatment
Otitis treatment
Safe
Safe and effective
Safe for otitis media treatment
Cephalexin less effective
Digestive issues
Digestive organ side effects
Digestive organ symptoms
Digestive side effects

Cefroxadine was found to be equally or more effective than cephalexin in treating ear infections, with similar safety profiles.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

15.

[Clinical evaluation of cefpodoxime proxetil in the treatment of skin and soft tissue infections. A double blind comparison of cefpodoxime proxetil and cefaclor].

Author: YuraJ, ShinagawaN, MizunoA, WatanabeS, AndoM, SakaiK, UedaT, MorimotoK, NakamuraT, HashimotoI

Bacteriologically effective
Effective for skin infections
Abnormal lab values
GI side effects

Cefpodoxime proxetil (CPDX-PR) was as effective as cefaclor (CCL) in treating skin and soft tissue infections in 243 patients. Both drugs were well tolerated, with no significant differences in side effects or usefulness.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Language : Japanese

16.

Double-blind, double-dummy comparison of azithromycin and cephalexin in the treatment of skin and skin structure infections.

Author: KianiR

5-day treatment effective
Antibacterial activity
Azithromycin effective
Bacteriological efficacy
Bacteriological eradication
Clinical efficacy
Clinical response
Effective skin infection treatment
Effective treatment
Infection treatment
Skin infection treatment
Well tolerated
Gastrointestinal disturbance
Gastrointestinal disturbances
Gastrointestinal issues
Gastrointestinal side effects
Treatment withdrawal

This study compared azithromycin and cephalexin in treating skin and skin structure infections. Both antibiotics were effective, with comparable outcomes in terms of clinical and bacteriological response. Azithromycin's 5-day regimen proved equally effective as cephalexin's 10-day regimen, demonstrating a potential benefit in terms of treatment duration.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

17.

[Clinical trials of BRL 25000 (clavulanic acid-amoxicillin) granules on skin and soft tissue infections in the field of pediatrics].

Author: MotohiroT, TanakaK, KogaT, ShimadaY, TomitaN, NishiyamaT, IshimotoK, TominagaK, IrikiT, HaradaM

Antibacterial activity
Antibacterial effect
BRL 25000 effective against S. aureus
BRL 25000 effectiveness
Cutaneous/soft tissue infection treatment
Effective against S. aureus
Effective against infections
Effective against skin infections
Effective cutaneous/soft tissue infections
Effective cutaneous/soft tissue infections treatment
Effective for soft tissue infections
Effective skin infection treatment
Effective skin infections
Potent antibacterial
Potent antibacterial activity
Gastrointestinal issues
Gastrointestinal side effects
Gastrointestinal upset
Minor side effects
No side effects

BRL 25000 (amoxicillin and clavulanate) was effective against skin/soft tissue infections in children, particularly S. aureus, with few side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

23.

Three-day therapy with cephalexin for lower urinary tract infections in children.

Author: HelinI

Cephalexin effective for UTIs
Cephalexin effectiveness
Cephalexin safe
Effective UTI treatment
Effective against UTI
Effective for UTI
Effective for urinary tract infections
Effective lower UTI treatment
Effective lower urinary tract infections
Effective urinary tract infections treatment
Lower urinary tract infection treatment
Safe and effective
Safe for lower urinary tract infections
Short course
Urinary tract infection treatment
Urinary tract treatment
Nitrofurantoin less effective
Relapse

In a study of children with urinary tract infections, a 3-day cephalexin course was as effective as a 10-day nitrofurantoin course (90% vs. 96% cure rates), with no side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

24.

Comparative treatment trial of augmentin versus cefaclor for acute otitis media with effusion.

Author: OdioC M, KusmieszH, SheltonS, NelsonJ D

Acute otitis media treatment
Amoxicillin-clavulanate effectiveness
Augmentin effective for acute otitis media
Effective acute otitis media treatment
Effective against otitis media
Effective for acute otitis media
Effective otitis media
Effective otitis media treatment
Otitis media treatment
Abdominal pain
Adverse effects
Augmentin more side effects
Cefaclor less effective
Diaper rash
Gastrointestinal side effects
Loose stools
Severe abdominal pain
Side effects
Stool issues
Vomiting

Amoxicillin-clavulanate was better than cefaclor for treating acute otitis media in children (no treatment failures vs. 8%), but it caused more side effects (diarrhea and rash).

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

25.

[Clinical studies of S6472 in otorhinolaryngologic infections].

Author: BabaS, KinoshitaH, MoriY, SuzukiK, OhyamaM, KatsutaK, FurutaS, OhnoI, NoboruT, YamamotoM

Effective otorhinolaryngology treatment
Mild side effects
Transient lab abnormalities

S6472, a long-acting preparation of cefaclor, was effective in 65.8% of 114 patients with otorhinolaryngology infections, particularly tonsillitis, with mild side effects.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

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