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Randomised controlled trial of the treatment of hyperlipidaemia on progression of atherosclerosis.

Author: LewisB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study of 25 men with symptomatic femoral atherosclerosis found that treatment for high cholesterol levels (including diet and medication) resulted in a slower progression of arterial disease compared to standard care. Treatment led to a 19% reduction in cholesterol and 37% reduction in triglyceride levels. Arteriography, performed after 19 months, showed that the treated group had less arterial disease progression and more instances of segmental disease regression compared to the control group. This suggests that effective treatment of high cholesterol can positively impact the progression of atherosclerosis.
Paper Details　
Original Abstract of the Article :
Two types of end-point measurement are presently available in clinical trials of the effect of treatment of hyperlipidaemia on cardiovascular disease; these are the incidence of clinical events and the arteriographic assessment of progression or regression of atherosclerosis. These approaches are br...See full text at original site
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引用元：
https://doi.org/10.1111/j.0954-6820.1985.tb08889.x

データ提供：米国国立医学図書館（NLM）

A Lipid-Lowering Oasis: Fighting Atherosclerosis

Atherosclerosis, a condition marked by the buildup of plaque in arteries, is a major health concern. This study explores the impact of treating hyperlipidaemia, high cholesterol, on the progression of atherosclerosis. Researchers investigated the effects of individualized lipid-lowering treatment on 25 men with symptomatic femoral atherosclerosis. They meticulously analyzed the changes in their arterial disease progression over a mean period of 19 months.

Lowering Cholesterol: A Promising Strategy

The study found that effective treatment of hyperlipidaemia led to a lower rate of progression of arterial disease and a higher frequency of segmental regression in the treated patients. This suggests that lowering cholesterol levels could be a valuable strategy for managing atherosclerosis. It's like finding a hidden oasis in the desert, where the right measures can help to reverse the effects of a harsh environment.

Maintaining Heart Health: A Desert Journey

This research emphasizes the importance of managing cholesterol levels for maintaining heart health. It's a journey that requires ongoing vigilance, like navigating a vast desert, but with the right tools and strategies, we can prevent the development of serious health problems.

Dr. Camel's Conclusion

This study provides compelling evidence that treating hyperlipidaemia can effectively manage atherosclerosis. It's like finding a hidden oasis in the desert, where the right measures can help to reverse the effects of a harsh environment. This research highlights the importance of maintaining healthy cholesterol levels as a crucial step in safeguarding cardiovascular health.

Date :
  1. Date Completed 1986-01-15
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

3907295

DOI: Digital Object Identifier

10.1111/j.0954-6820.1985.tb08889.x

Related Literature

Article Analysis
・Effective treatment of atherosclerosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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