Glipizide: a second-generation sulfonylurea hypoglycemic agent. Pharmacology, pharmacokinetics and clinical use.

Author: LebovitzH E

Paper Details 
Original Abstract of the Article :
Glipizide is a second-generation sulfonylurea in which the substitutions on the arylsulfonylurea nucleus are large, relatively nonpolar groups. This chemical change increases the intrinsic hypoglycemic activity of the molecule 100-fold on a weight basis compared to first-generation agents. In additi...See full text at original site
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引用元:
https://doi.org/10.1002/j.1875-9114.1985.tb03405.x

データ提供:米国国立医学図書館(NLM)

The Power of Glipizide in Diabetes Management

Diabetes, a chronic condition affecting millions worldwide, presents a significant challenge in the field of medicine. Researchers are constantly seeking new and improved treatments to effectively manage blood sugar levels and improve the quality of life for individuals living with diabetes. This study focuses on a second-generation sulfonylurea hypoglycemic agent called glipizide, exploring its pharmacological properties and clinical applications in the treatment of diabetes.

Glipizide: A Powerful Weapon Against Hyperglycemia

Glipizide, a second-generation sulfonylurea, has demonstrated significant advantages over its first-generation counterparts. Its enhanced intrinsic hypoglycemic activity, combined with favorable pharmacokinetic properties, makes it a potent tool for controlling blood sugar levels in patients with noninsulin-dependent diabetes mellitus. The researchers found that glipizide is at least as effective as, and potentially more effective than, first-generation sulfonylureas in managing hyperglycemia. These findings highlight the potential benefits of glipizide in improving diabetes management and overall patient outcomes.

Managing Diabetes for a Healthier Life

Diabetes is a complex condition that requires careful monitoring and management. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan for your individual needs. Maintaining a healthy lifestyle, including regular exercise and a balanced diet, plays a vital role in managing diabetes. The research on glipizide suggests that this medication may be a valuable tool in achieving optimal blood sugar control and improving the overall health and well-being of individuals with diabetes.

Dr.Camel's Conclusion

Just as a camel adapts to the harsh desert environment, those living with diabetes must adapt to the challenges of their condition. This research on glipizide offers a new approach to diabetes management, providing a powerful tool for controlling blood sugar levels. The desert of diabetes may be vast and unforgiving, but with knowledge, perseverance, and effective treatments, individuals can navigate this journey towards a healthier life.

Date :
  1. Date Completed 1985-06-24
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

3923454

DOI: Digital Object Identifier

10.1002/j.1875-9114.1985.tb03405.x

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PICO Info
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Languages

English

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