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Treatment of hypertension in the elderly.

Author: DrayerJ I, WeberM A

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Guanabenz, a centrally acting antihypertensive agent, was effective in treating predominant systolic hypertension in elderly patients. Both guanabenz alone and in combination with hydrochlorothiazide significantly decreased systolic and diastolic blood pressures, with no evidence of orthostatic effects. The most common side effects were drowsiness and dry mouth.
Paper Details　
Original Abstract of the Article :
We have evaluated the effectiveness of antihypertensive therapy for predominant systolic hypertension in 55 patients, aged 61 to 76 years, with untreated systolic blood pressures of at least 160 mm Hg and diastolic blood pressures less than 100 mm Hg. In this retrospective analysis, 41 of the patien...See full text at original site
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引用元：
https://doi.org/10.1097/00007611-198603000-00016

データ提供：米国国立医学図書館（NLM）

Treating Hypertension in the Elderly: A Journey Through the Sands of Time

The desert of aging brings its own unique challenges, and hypertension is a common ailment among the elderly. This research delves into the effectiveness of antihypertensive therapy in older adults with predominant systolic hypertension. The authors evaluated the efficacy and tolerability of guanabenz, a centrally acting agent, either alone or in combination with hydrochlorothiazide.

Finding Oasis in the Desert of Hypertension

The study demonstrated that both guanabenz alone and guanabenz in combination with hydrochlorothiazide effectively reduced both systolic and diastolic blood pressure in elderly patients. The researchers found no significant differences in efficacy between the two regimens, and the side effects were generally mild and well-tolerated.

Navigating the Challenges of Hypertension

The research provides valuable insights for clinicians treating hypertension in older adults. It highlights the potential benefits of guanabenz as an effective and well-tolerated treatment option, particularly in cases of predominant systolic hypertension.

Dr.Camel's Conclusion

The journey through the desert of aging can be challenging, but effective treatment options can help us navigate the path to better health. This study provides valuable information for clinicians seeking to manage hypertension in elderly patients and offers hope for a healthier and more fulfilling life in our later years.

Date :
  1. Date Completed 1986-04-16
  2. Date Revised 2019-07-02
Further Info :

Pubmed ID

3952544

DOI: Digital Object Identifier

10.1097/00007611-198603000-00016

Related Literature

Article Analysis
・Side Effects of guanabenz
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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