[Effect of aztreonam on bacterial flora in human feces].

Author: AramakiM, FujimotoT, KawakamiA, KogaT, MotohiroT, NishiyamaT, SakataY, ShimadaY, TanakaK, TomitaN

Paper Details 
Original Abstract of the Article :
Aztreonam (AZT), a new injectable monobactam antibiotic, was administered to 7 healthy male volunteers, aged 21-28 years (23 years, on average) and weighing 60.5-87.0 kg, (69.5 kg, on average) by one shot intravenous injection of 1,000 mg twice a day for 5 days. The effect of AZT on the fecal flora ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/4094070

データ提供:米国国立医学図書館(NLM)

Aztreonam: A Powerful Antibiotic, But Effects on Gut Bacteria Require Careful Monitoring

Aztreonam, like a powerful desert wind, is a potent antibiotic that effectively combats bacterial infections. This study investigates the impact of aztreonam on the bacterial flora in human feces, revealing a complex interplay between this antibiotic and the delicate balance of gut bacteria. The researchers administered aztreonam to healthy volunteers, carefully monitoring changes in their fecal flora over time. The study's findings reveal that aztreonam, like a desert sandstorm, can significantly disrupt the composition of gut bacteria. While it effectively reduced the population of Enterobacteriaceae, it also led to the emergence of other bacterial strains, highlighting the importance of carefully monitoring gut health during aztreonam treatment. The study emphasizes the need for personalized approaches to antibiotic therapy, recognizing that the impact of antibiotics on gut bacteria can vary significantly between individuals.

Aztreonam: A Double-Edged Sword in the Fight Against Infection

This study reveals the complex impact of aztreonam on gut bacteria, highlighting both its effectiveness in combating infections and its potential to disrupt the delicate balance of this vital ecosystem. The study underscores the importance of personalized approaches to antibiotic therapy, recognizing that the effects of antibiotics can vary significantly between individuals.

Navigating the Complexities of Antibiotic Therapy

Antibiotics, like powerful desert winds, can have a profound impact on the body's delicate ecosystem. This study highlights the importance of carefully monitoring gut health during antibiotic treatment, ensuring that the benefits of these medications outweigh any potential side effects.

Dr. Camel's Conclusion

Aztreonam, like a potent desert wind, can effectively combat bacterial infections. This study reveals the complex impact of this antibiotic on the delicate balance of gut bacteria, emphasizing the importance of personalized approaches to antibiotic therapy and careful monitoring of gut health during treatment.

Date :
  1. Date Completed 1986-04-21
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

4094070

DOI: Digital Object Identifier

4094070

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Languages

Japanese

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