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Cromolyn effects on vernal keratoconjunctivitis in children.

Author: ArafatN T, TabbaraK F

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Topical cromolyn sodium eye drops were effective in reducing symptoms of vernal keratoconjunctivitis in children. It reduced vernal keratitis, corneal ulcers and plaques, limbal edema, and infiltrates but did not affect giant papillae.
Paper Details　
Original Abstract of the Article :
A double-masked, coded trial was undertaken to evaluate the effect of the topical administration of 2% cromolyn sodium eye drops on vernal keratoconjunctivitis in 14 children. One eye of each patient was treated for one year with cromoly, the other eye with placebo. Cromolyn reduced the characterist...See full text at original site
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引用元：
https://doi.org/10.1001/archopht.1977.04450120090009

データ提供：米国国立医学図書館（NLM）

Cromolyn: A Oasis in the Desert of Vernal Keratoconjunctivitis

Vernal keratoconjunctivitis (VKC), a debilitating eye condition, can feel like a desert storm, bringing intense itching, inflammation, and vision problems. This study investigates the potential of cromolyn sodium eye drops as a therapeutic option for children with VKC. The researchers conducted a double-masked, coded trial to assess the effectiveness of cromolyn in treating VKC symptoms.

Cromolyn's Impact on VKC Symptoms

The study found that cromolyn was effective in reducing the characteristic symptoms of VKC, including corneal ulcers, plaques, and limbal edema and infiltrates. However, it did not have a significant impact on the number or size of giant papillae. These findings suggest that cromolyn could offer a valuable treatment option for VKC, although it may not fully address all aspects of the condition.

Finding Relief from VKC

VKC can significantly impact a child's quality of life, making it difficult to participate in everyday activities. This study provides hope for finding relief from VKC symptoms. Cromolyn's ability to reduce inflammation and discomfort may improve a child's vision and overall well-being. Just as a cool breeze can bring respite in a scorching desert, cromolyn may offer a similar sense of relief to children suffering from VKC.

Dr.Camel's Conclusion

This study offers promising evidence for the potential of cromolyn sodium eye drops as a treatment for VKC in children. While further research is needed to fully understand its effectiveness and long-term impact, it provides a potential oasis in the desert of VKC, offering hope for improved vision and quality of life for those affected by this condition.
Date :
  1. Date Completed 1978-01-27
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

412489

DOI: Digital Object Identifier

10.1001/archopht.1977.04450120090009

Related Literature

Article Analysis
・Side Effects of cromolyn ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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