External ocular toxicity of dipivalyl epinephrine.

Author: LeibowitzH M, TheodoreJ

Paper Details 
Original Abstract of the Article :
Of 26 patients enrolled in a study designed to assess the usefulness of dipivalyl epinephrine 0.1%, administered topically at 12-hour intervals, for lowering intraocular pressure in patients with glaucoma and ocular hypertension, six patients (23.1%) developed adverse external ocular side effects se...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9394(79)90407-0

データ提供:米国国立医学図書館(NLM)

Dipivalyl Epinephrine: A Potential Oasis or a Mirage?

The treatment of glaucoma and ocular hypertension is like navigating a desert of vision loss. Dipivalyl epinephrine, a topical medication, is one such oasis, promising to lower intraocular pressure and potentially prevent vision loss. However, this study, a clinical trial evaluating the safety and efficacy of dipivalyl epinephrine, discovered some potential mirages. While many patients experienced positive effects, a significant number developed severe external ocular side effects, requiring discontinuation of the medication. This highlights the importance of careful monitoring and individualized approach to treatment.

Navigating the Desert of Side Effects: A Case-by-Case Approach

This research emphasizes that while dipivalyl epinephrine can be a valuable tool for managing glaucoma and ocular hypertension, it's not a universal solution. The study found that a history of epinephrine intolerance, even when successfully using other forms of epinephrine in the past, increased the risk of adverse reactions. The data also suggests that the duration of exposure may play a role in developing sensitivity to dipivalyl epinephrine.

Finding the Right Oasis: Careful Observation is Key

The study highlights the importance of individualizing treatment approaches for glaucoma and ocular hypertension. Patients with a history of epinephrine intolerance should be carefully monitored and alternative treatments may be considered. Regular eye examinations and close communication with your ophthalmologist are crucial to ensure a safe and effective treatment journey, navigating the desert of potential side effects.

Dr.Camel's Conclusion

This study reinforces the need for a cautious approach when using dipivalyl epinephrine to manage glaucoma and ocular hypertension. It highlights the importance of considering individual patient factors and carefully monitoring potential side effects. Just like navigating a desert, finding the right oasis for your vision health requires a careful journey with experienced guides.

Date :
  1. Date Completed 1980-02-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

517603

DOI: Digital Object Identifier

10.1016/0002-9394(79)90407-0

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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