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A double blind comparison of viloxazine and amitryptyline in involutional and endogenous depression.

Author: BotterP A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Viloxazine was equally effective as amitriptyline in treating endogenous depression and significantly more effective in involutional depression. Viloxazine caused less anticholinergic side effects than amitriptyline.
Paper Details　
Original Abstract of the Article :
Thirty-two hospitalized patients with either endogenous (n = 15) or involutional (n = 17) depression were entered into a double blind study to compare the effectiveness and acceptability of viloxazine with amitriptyline. The severity of the depression was assessed before starting treatment and at da...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/532690

データ提供：米国国立医学図書館（NLM）

Comparing Viloxazine and Amitriptyline for Depression

This study investigates the effectiveness of two different antidepressants, viloxazine and amitriptyline, in treating depression. It compares their effectiveness in both endogenous and involutional depression, which are two distinct types of depression. This research is essential in understanding the nuances of depression and finding the best treatment options for different individuals.

Navigating the Desert of Depression

The study found that viloxazine and amitriptyline were equally effective in treating endogenous depression. However, viloxazine proved to be significantly more effective in patients with involutional depression. This suggests that the choice of antidepressant may depend on the specific type of depression being treated. It's like finding the right path through a diverse and challenging desert landscape.

Finding the Right Treatment for Depression

This research highlights the importance of choosing the right treatment for depression. It emphasizes that not all antidepressants work the same way for everyone. If you're struggling with depression, it's essential to talk to your doctor and find a treatment plan that's tailored to your individual needs. Remember, you're not alone in this journey – there are many resources available to help you navigate the desert of depression.

Dr.Camel's Conclusion

This study provides valuable insights into the treatment of depression, revealing that different antidepressants may be more effective for specific types of depression. It's crucial to find a treatment plan that fits your individual needs. Like a camel adapting to the desert environment, finding the right treatment can make a world of difference in managing depression.
Date :
  1. Date Completed 1980-04-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

532690

DOI: Digital Object Identifier

532690

Related Literature

Article Analysis
・Side Effects of viloxazine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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