Paper Details

  1. Home
  2. Paper Details

The treatment of gout and disorders of uric acid metabolism with allopurinol.

Author: HouptJ B, OgryzloM A, UrowitzM B, WeberH M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Allopurinol effectively lowered serum uric acid in 80 patients with gout and other uric acid disorders. It increased oxypurine excretion and had minimal side effects.
Paper Details　
Original Abstract of the Article :
Allopurinol (4-hydroxypyrazolo (3,4-d)-pyrimidine) is a potent xanthine oxidase inhibitor which inhibits the oxidation of naturally occurring oxypurines, thus decreasing uric acid formation. The clinical and metabolic effects of this agent were studied in 80 subjects with primary and secondary gout ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935821/

データ提供：米国国立医学図書館（NLM）

The Treatment of Gout and Disorders of Uric Acid Metabolism with Allopurinol

Gout, a painful inflammatory condition caused by the buildup of uric acid in the body, is a common health concern. This research investigates the effectiveness of allopurinol, a medication that inhibits the production of uric acid, in treating gout and other disorders of uric acid metabolism. The study involved 80 patients with primary and secondary gout, evaluating the effects of allopurinol on serum uric acid levels and uric acid excretion. The findings demonstrate that allopurinol is highly effective in lowering uric acid levels and improving gout symptoms, making it a valuable treatment option for this condition.

Allopurinol for Gout Treatment

This research underscores the effectiveness of allopurinol in treating gout and other disorders of uric acid metabolism. The study found that allopurinol consistently lowered serum uric acid levels to normal, while not significantly affecting other aspects of renal function. This information highlights the importance of allopurinol as a cornerstone treatment for gout, helping to reduce symptoms and prevent complications.

Managing Uric Acid Levels

This research provides valuable insights for managing gout and other disorders of uric acid metabolism. The findings demonstrate the effectiveness of allopurinol in lowering uric acid levels and improving patient outcomes. This information emphasizes the importance of early diagnosis and appropriate treatment with medications like allopurinol to control uric acid levels and prevent complications.

Dr. Camel's Conclusion

Just like a camel adapts to the desert's scarcity of water, doctors need to find effective ways to manage the excess uric acid that can cause gout. This research highlights the crucial role of allopurinol in treating gout and other disorders of uric acid metabolism. By understanding the effectiveness and safety of allopurinol, doctors can help patients manage their condition and improve their quality of life.

Date :
  1. Date Completed 1967-01-28
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

5923471

DOI: Digital Object Identifier

PMC1935821

Related Literature

Article Analysis
・Side Effects of sulfinpyrazone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.