Paper Details 
Original Abstract of the Article :
Nineteen patients (12 male and seven female) with essential hypertension (mean arterial pressure ranging from 113-162 mmHg) were studied at rest, supine and sitting, and during bicycle exercise (50, 100 and 150 W). Intra-arterial blood pressure and heart rate were recorded continuously. Cardiac outp...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6100877

データ提供:米国国立医学図書館(NLM)

Long-Term Effects of Enalapril on Blood Pressure and Hemodynamics

In the world of [hypertension management], understanding the long-term effects of medications is critical. This study investigates the impact of enalapril, a commonly used antihypertensive medication, on blood pressure and hemodynamics both at rest and during exercise. The study included 19 patients with essential hypertension who received enalapril alone or in combination with hydrochlorothiazide for a period of 5 to 13 months. Researchers meticulously measured various cardiovascular parameters, including blood pressure, heart rate, cardiac output, and total peripheral resistance index (TPRI).

Enalapril's Impact on Blood Pressure and Resistance

The study revealed that enalapril effectively reduced blood pressure both at rest and during exercise. Significantly, the TPRI, a measure of resistance in blood vessels, also decreased in patients treated with enalapril. In patients receiving enalapril in combination with hydrochlorothiazide, the reduction in TPRI was even more pronounced. This suggests that the combination therapy may be more effective in reducing vascular resistance, ultimately leading to better blood pressure control.

Enalapril's Long-Term Effects and Cardiovascular Health

These findings highlight the potential of enalapril as a long-term medication for managing hypertension. The observed reduction in blood pressure and vascular resistance can contribute to [improved cardiovascular health]. However, it is crucial to consider [potential side effects] and individual patient needs when deciding on the best course of treatment.

Dr. Camel's Conclusion

This study offers valuable insights into the long-term effectiveness of enalapril in managing hypertension. Like a camel who endures the harsh desert environment, enalapril can help individuals with hypertension navigate their journey towards better cardiovascular health. The research emphasizes the importance of personalized treatment approaches and careful monitoring of cardiovascular parameters for optimal outcomes.

Date :
  1. Date Completed 1987-02-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6100877

DOI: Digital Object Identifier

6100877

SNS
PICO Info
in preparation
Languages

English

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