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Effects of tetrabenazine and phenylpiperidine analgesics during daily clorgyline treatment.

Author: LeanderJ D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Clorgyline decreased responding in pigeons under a multiple schedule of food presentation, with tetrabenazine having no effect or decreasing responding under chronic clorgyline. Clorgyline increased sensitivity to morphine's effects but not to other opioids.
Paper Details　
Original Abstract of the Article :
Pigeons responded under a multiple fixed-ratio 30-response, fixed-interval 5-min schedule of food presentation. Daily administration of clorgyline (10 mg/kg, IM) tended to decrease rates of responding in both schedule components. Before daily clorgyline, tetrabenazine had no effect or decreased resp...See full text at original site
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引用元：
https://doi.org/10.1007/BF00427098

データ提供：米国国立医学図書館（NLM）

Effects of Tetrabenazine and Phenylpiperidine Analgesics on Pigeons

This research delves into the intricate world of neuropharmacology, exploring the effects of various medications on pigeons. It utilizes a sophisticated experimental paradigm involving fixed-ratio and fixed-interval schedules of food presentation, offering a detailed analysis of the drug's effects on behavior. This study is like a careful observation of a flock of birds in the desert, understanding their movements and responses to different stimuli.

The Influence of Medications on Behavior

The study examines the influence of tetrabenazine, a medication used to treat movement disorders, and several phenylpiperidine analgesics on pigeons' behavior. It reveals that tetrabenazine has varying effects depending on the presence of clorgyline, a drug affecting the nervous system. This intricate interplay of medication effects is akin to the intricate web of relationships in a desert ecosystem.

A Deeper Understanding of Drug Interactions

This research provides valuable insights into the complex interactions between medications and their effects on behavior. It highlights the importance of understanding these interactions, much like a desert traveler must be aware of the different risks and opportunities presented by the changing landscape.

Dr.Camel's Conclusion

This study offers a fascinating glimpse into the intricate world of drug interactions and their effects on behavior. It reminds us that the world of pharmacology is complex, like a vast desert landscape, requiring a careful understanding of each component to navigate the complexities effectively.

Date :
  1. Date Completed 1981-10-25
  2. Date Revised 2019-07-26
Further Info :

Pubmed ID

6115448

DOI: Digital Object Identifier

10.1007/BF00427098

Related Literature

Article Analysis
・Effects of tetrabenazine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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