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[Comparative studies of initial pressure reduction using 0.3% metipranolol and 0.25% timolol in eyes with wide-angle glaucoma].

Author: MertzM, MertéH J, StryzJ R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Metipranolol and Timolol, both beta-blockers, had similar pressure-lowering effects and duration of action.
Paper Details　
Original Abstract of the Article :
In a short-term study the pressure-lowering effects of Metipranolol 0.3% and Timolol 0.25% were compared in eyes with open-angle glaucoma by means of one-drop curves, diurnal pressure curves and tonography. It appears that these two drugs may be regarded as equal in respect of extent and duration of...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6134861

データ提供：米国国立医学図書館（NLM）

Comparing Pressure Reduction: Metipranolol vs. Timolol in Glaucoma

Ophthalmology, the study of the eye, is a fascinating field with a constant quest for better treatments. This research compares the effectiveness of two medications, metipranolol and timolol, in reducing intraocular pressure in patients with wide-angle glaucoma. The authors analyzed the pressure-lowering effects of these medications over time, providing valuable insights into their effectiveness and potential for managing glaucoma.

Metipranolol vs. Timolol: A Side-by-Side Comparison

The study demonstrates that metipranolol and timolol have similar pressure-lowering effects, both in terms of extent and duration of action. Both medications were found to facilitate aqueous humor outflow, although the increase was statistically significant only with metipranolol.

Managing Glaucoma: Finding the Right Treatment Approach

This research highlights the importance of carefully considering the various treatment options available for glaucoma. The study suggests that both metipranolol and timolol can be effective in reducing intraocular pressure, but the choice of medication may depend on individual patient characteristics and preferences.

Dr.Camel's Conclusion

This study provides a valuable comparison of metipranolol and timolol for managing intraocular pressure in patients with wide-angle glaucoma. The findings suggest that both medications are effective and that the choice between them may be based on individual factors.

Date :
  1. Date Completed 1983-08-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6134861

DOI: Digital Object Identifier

6134861

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in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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