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Original Abstract of the Article :
A depressed patient developed neuroleptic-like side effects while being treated with amoxapine alone. Elevation of he...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1176/ajp.140.9.1233
データ提供:米国国立医学図書館(NLM)
Amoxapine: Navigating the Desert of Side Effects
Amoxapine, a medication used to treat depression, has a unique profile that combines antidepressant and antipsychotic properties. This case report highlights the potential for amoxapine to cause neuroleptic-like side effects, which are associated with antipsychotic medications.
Amoxapine: A Case of Unexpected Side Effects
The report describes a patient who developed neuroleptic-like side effects while being treated with amoxapine alone. The patient's plasma prolactin level, a hormone that is often elevated by antipsychotic medications, was found to be increased, and ex vivo neuroleptic activity was detected. This suggests that amoxapine can indeed produce neuroleptic-like effects, even at therapeutic doses.
Navigating the Desert of Side Effects
This case report underscores the importance of careful monitoring for potential side effects when prescribing amoxapine. The patient's experience highlights the need to be aware of the unique properties of this medication and to consider the possibility of neuroleptic-like side effects, especially in individuals with a history of sensitivity to antipsychotic medications.
Dr. Camel's Conclusion
This case report provides a reminder that even medications with a specific intended purpose, like amoxapine, can have unexpected side effects. It emphasizes the importance of close monitoring and a thorough understanding of the potential risks and benefits of any medication. The report also highlights the need for further research to understand the mechanisms underlying amoxapine's neuroleptic-like effects.
Date :
- Date Completed 1983-10-08
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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