Amoxapine and neuroleptic side effects: a case report.

Author: CohenB M, OrsulakP J, SunderlandT

Paper Details 
Original Abstract of the Article :
A depressed patient developed neuroleptic-like side effects while being treated with amoxapine alone. Elevation of he...See full text at original site
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引用元:
https://doi.org/10.1176/ajp.140.9.1233

データ提供:米国国立医学図書館(NLM)

Amoxapine: Navigating the Desert of Side Effects

Amoxapine, a medication used to treat depression, has a unique profile that combines antidepressant and antipsychotic properties. This case report highlights the potential for amoxapine to cause neuroleptic-like side effects, which are associated with antipsychotic medications.

Amoxapine: A Case of Unexpected Side Effects

The report describes a patient who developed neuroleptic-like side effects while being treated with amoxapine alone. The patient's plasma prolactin level, a hormone that is often elevated by antipsychotic medications, was found to be increased, and ex vivo neuroleptic activity was detected. This suggests that amoxapine can indeed produce neuroleptic-like effects, even at therapeutic doses.

Navigating the Desert of Side Effects

This case report underscores the importance of careful monitoring for potential side effects when prescribing amoxapine. The patient's experience highlights the need to be aware of the unique properties of this medication and to consider the possibility of neuroleptic-like side effects, especially in individuals with a history of sensitivity to antipsychotic medications.

Dr. Camel's Conclusion

This case report provides a reminder that even medications with a specific intended purpose, like amoxapine, can have unexpected side effects. It emphasizes the importance of close monitoring and a thorough understanding of the potential risks and benefits of any medication. The report also highlights the need for further research to understand the mechanisms underlying amoxapine's neuroleptic-like effects.

Date :
  1. Date Completed 1983-10-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6137151

DOI: Digital Object Identifier

10.1176/ajp.140.9.1233

Related Literature

SNS
PICO Info
in preparation
Languages

English

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