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Respiratory and sedative effects of triazolam in volunteers.

Author: LongbottomR T, PleuvryB J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Triazolam caused dose-dependent sedation but did not significantly decrease ventilatory response to carbon dioxide. The effects of triazolam 0.5 mg on sedation and cognitive function persisted for 6 hours.
Paper Details　
Original Abstract of the Article :
Two oral doses of triazolam, 0.5 mg and 0.25 mg, have been compared with placebo in respect of their effects on ventilation, ventilatory response to carbon dioxide, heart rate, arterial pressure, sedation and performance in a variety of psychological tests in 12 healthy volunteers. The study was dou...See full text at original site
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引用元：
https://doi.org/10.1093/bja/56.2.179

データ提供：米国国立医学図書館（NLM）

Triazolam: Respiratory and Sedative Effects

The field of [pharmacology] investigates the [effects of drugs] on [human physiology]. This research examines the [respiratory and sedative effects] of [triazolam] in [healthy volunteers]. The authors found that [triazolam produced dose-dependent sedation] but did [not significantly decrease] the [ventilatory response to carbon dioxide].

Triazolam: Sedative Effects and Respiratory Considerations

The study reveals that [triazolam] can [induce sedation] and [affect cognitive function]. It highlights the [importance of monitoring respiratory function] and [potential risks] associated with [triazolam use].

Safe Medication Use: Understanding Potential Risks

It is crucial to [be aware of the potential risks and side effects] of [medications] and to [consult with healthcare providers] about [appropriate use]. This research emphasizes the [importance of responsible medication use] to [ensure safety and well-being].

Dr.Camel's Conclusion

Imagine a desert traveler, weary from a long journey, seeking respite from the scorching sun. Just as a traveler might seek the calming effects of a cool breeze, individuals might turn to medications like triazolam for relief. This research explores the effects of triazolam on the body, highlighting the importance of understanding its sedative properties and potential impact on respiratory function. Remember, like a wise desert traveler, we must approach medications with caution, understanding their potential benefits and risks to ensure our well-being.
Date :
  1. Date Completed 1984-03-23
  2. Date Revised 2019-05-15
Further Info :

Pubmed ID

6140935

DOI: Digital Object Identifier

10.1093/bja/56.2.179

Related Literature

Article Analysis
・Effects of triazolam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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