Effects of triazolam: A Synthesis of Findings from 25 Studies

  1. Home
  2. Effects of triazolam
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Effects of triazolam: A Synthesis of Findings from 25 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Effects of triazolam: A Synthesis of Findings from 25 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Major Research Findings

Triazolam has been shown to be effective in treating insomnia in several studies. 3 , 2 Triazolam improved sleep quality compared to placebo and secobarbital, demonstrating its effectiveness for sleep. 3 It was superior to placebo or secobarbital in terms of sleep parameters like time to fall asleep, total sleep time, and the number of awakenings during the night. 3 While improving sleep quality, triazolam did not impact alertness the next morning. 3 Triazolam may affect memory and psychomotor function. 16 , 23 Additionally, higher doses or long-term use might increase the risk of dependence, tolerance, and withdrawal symptoms. 8 , 7 Triazolam, compared to other sleep medications, tends to act faster and has a shorter duration of effect. 13 , 11 Triazolam is reported to have less morning-after effects compared to other sleep medications. 11 For elderly individuals, the effects of triazolam may last longer due to slower metabolism. 5 Furthermore, triazolam can interact with other medications. 20

Benefits and Risks

Benefit Summary

Triazolam is an effective drug for treating insomnia, and it is expected to improve sleep quality. 3 It offers advantages over other sleep medications, including a fast onset of action and fewer morning-after effects. 13 , 11

Risk Summary

Triazolam may affect memory and psychomotor function. 16 , 23 Higher doses or long-term use may increase the risk of dependence, tolerance, and withdrawal symptoms. 8 , 7 Elderly individuals may experience prolonged effects due to slower metabolism. 5 Additionally, it can interact with other medications. 20

Comparison Across Studies

Commonalities Among Studies

Multiple studies have shown that triazolam is effective in treating insomnia. 3 , 2 Moreover, triazolam has been shown to improve sleep quality compared to placebo and other sleep medications. 3 , 2

Differences Across Studies

There are discrepancies in research findings regarding triazolam's side effects and efficacy. Some studies report that triazolam does not impact memory or psychomotor function. 3 Conversely, other studies report that triazolam can affect memory and psychomotor function. 16 , 23 Similarly, research findings on dependence, tolerance, and withdrawal symptoms associated with triazolam vary across studies. 8 , 7

Consistency and Contradictions in Findings

While multiple studies demonstrate triazolam's effectiveness in treating insomnia, 3 , 2 research findings on its side effects and efficacy show some discrepancies. 3 , 16 , 23 Triazolam is known for its fast onset and minimal morning-after effects, 13 , 11 however, high doses or long-term use raise concerns about dependence, tolerance, and withdrawal symptoms. 8 , 7 Hence, caution is needed when using triazolam.

Considerations for Real-World Application

Triazolam is an effective medication for insomnia, 3 , 2 but it may impact memory and psychomotor function. 16 , 23 Furthermore, high doses or prolonged use can lead to dependence, tolerance, and withdrawal symptoms. 8 , 7 Therefore, when using triazolam, it is crucial to follow your doctor's instructions and avoid self-medication.

Limitations of Current Research

Research on triazolam is still insufficient. Particularly, further investigation is required regarding its long-term effects and individual variations.

Future Research Directions

Further research is needed on triazolam's long-term effects, individual variations, and interactions with other medications. Additionally, research is necessary to explore methods for preventing dependence, tolerance, and withdrawal symptoms associated with triazolam.

Conclusion

Triazolam is an effective medication for treating insomnia, 3 , 2 but research findings on its side effects and efficacy exhibit some discrepancies. 3 , 16 , 23 Therefore, when using triazolam, it is essential to follow your doctor's instructions and avoid self-medication.

Literature analysis of 25 papers
Positive Content
17
Neutral Content
2
Negative Content
6
Article Type
25
0
0
0
25
1.

Hypnotic efficacy of triazolam and methyprylon ininsomniac in-patients.

Author: LomenP, LinetO I

Hypnotic effect

Triazolam, a triazolobenzodiazepine, was preferred by patients with insomnia over methyprylon. Triazolam helped patients sleep more, induced faster sleep onset, and provided longer sleep duration. Both drugs were well tolerated.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

2.

Preference studies of triazolam with standard hypnotics in out-patients with insomnia.

Author: FabreL F, McLendonD M, HarrisR T

Insomnia treatment
Side effects

Triazolam, a benzodiazepine, was superior to placebo, flurazepam, and chloral hydrate in treating insomnia in 104 patients. Triazolam was preferred by patients and showed better effects on sleep onset, duration, and awakenings. Side effects were minimal.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

3.

A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients.

Author: OkawaK K, AllensG S

Insomnia treatment
Mild side effects

Triazolam was found to be more effective than placebo and secobarbital in treating insomnia. In double-blind studies, patients reported better sleep onset, duration, and fewer awakenings with triazolam. There were no differences in alertness the next morning, and side effects did not significantly impact function.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

4.

Selective effects of triazolam on memory.

Author: WeingartnerH J, HommerD, ListerR G, ThompsonK, WolkowitzO

No effect on semantic memory
Impaired memory

Triazolam impaired free recall and recognition of information presented after drug administration but did not affect semantic memory or unconscious memory function.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

5.

Sensitivity to triazolam in the elderly.

Author: GreenblattD J, HarmatzJ S, ShapiroL, EngelhardtN, GouthroT A, ShaderR I

CNS depression

The effect of age on the pharmacokinetics and pharmacodynamics of triazolam, a benzodiazepine hypnotic agent, was investigated.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

6.

Dose-response evaluation of the amnestic effects of triazolam and pentobarbital in normal subjects.

Author: KirkT, RoacheJ D, GriffithsR R

Recall impairment

Both triazolam and pentobarbital were found to impair short-term recall performance in a dose-dependent manner. Triazolam was found to be 270-384 times more potent than pentobarbital in subject ratings and psychomotor measures, and 406-647 times more potent on measures of recall impairment. Triazolam also showed a greater tendency to interfere with retention over short delay intervals.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

7.

The effects of a single night's dosing with triazolam on sleep the following night.

Author: MamelakM, CsimaA, PriceV

Increased sleep duration
Withdrawal insomnia

A single night's use of 0.5 mg triazolam in normal sleepers led to withdrawal insomnia, while 0.25 mg did not, indicating a dose-response relationship.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

8.

Tolerance and rebound during and after short-term administration of quazepam, triazolam and placebo to healthy human volunteers.

Author: LeeA, LaderM

Improved sleep quality
Bodily symptoms
Sedation

Quazepam and triazolam both improved sleep quality in healthy volunteers, but had different effects on performance and side effects. Quazepam improved motor performance, while triazolam impaired it. Both drugs increased bodily symptoms and sedation.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

9.

Ventilatory effects of single, high-dose triazolam in awake human subjects.

Author: SkatrudJ B, BegleR L, BuschM A

Increased breathing frequency
No respiratory depression
None

Triazolam, a hypnotic, did not cause respiratory depression in normal subjects at doses two and three times the usual level. However, it altered respiratory cycle timing, increasing breathing frequency.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Language : English

10.

Morning amnestic effects of triazolam.

Author: ScharfM B, KauffmanR, BrownL, SegalJ J, HirschowitzJ

Amnestic effect

Triazolam had a statistically significant amnestic effect that extended beyond its hypnotic effect. The study found that the triazolam group showed a significant decrease in delayed recall compared to baseline at 0.5 and 8 hours after administration.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

11.

The effects of triazolam and nitrazepam on sleep quality, morning vigilance and psychomotor performance.

Author: HindmarchI, ClydeC A

Hypnotic effect
Impaired awakening
Impaired mental performance

Both triazolam and nitrazepam were effective hypnotics, but nitrazepam impaired early morning performance, while triazolam did not.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

12.

Residual and acute effects of flurazepam and triazolam in normal subjects.

Author: GorensteinC, GentilV

Induces sleep
Hangover
Sedation

Flurazepam and triazolam, both benzodiazepine hypnotics, produced similar hangover effects, impairing motor performance and increasing sleepiness the next morning. Triazolam caused more pronounced sedative effects than flurazepam when administered in the morning.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

13.

Comparison of the effects of intravenously administered midazolam, triazolam and their hydroxy metabolites.

Author: ZieglerW H, SchalchE, LeishmanB, EckertM

Induces sleep
Sedative effect
Hangover
Reduced cognitive function

Triazolam had the strongest and longest-lasting effect compared to midazolam and their hydroxy metabolites.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

14.

Respiratory and sedative effects of triazolam in volunteers.

Author: LongbottomR T, PleuvryB J

Induces sleep
Impaired cognitive function
Sedation

Triazolam caused dose-dependent sedation but did not significantly decrease ventilatory response to carbon dioxide. The effects of triazolam 0.5 mg on sedation and cognitive function persisted for 6 hours.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

15.

Double-blind crossover comparison of triazolam and lorazepam in the posthypnotic state.

Author: CohnJ B

Induces sleep
Daytime sleepiness
Side effects

Triazolam and lorazepam are both effective hypnotics, but lorazepam has more pronounced daytime carryover and side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

16.

Dissociations in the expression of the sedative effects of triazolam.

Author: WeingartnerH J, SiroccoK, RawlingsR, JoyceE, HommerD

Impaired memory
Sedation

Triazolam, a hypnotic drug, impaired free recall in healthy volunteers in a dose-dependent manner, suggesting an effect on reflective processes.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

17.

A comparison of the acute behavioral effects of triazolam and temazepam in normal volunteers.

Author: RushC R, HigginsS T, HughesJ R, BickelW K

Triazolam less disruptive
Temazepam more disruptive

Triazolam and temazepam both cause behavioral impairment and subjective effects, but temazepam may be more disruptive at higher doses, contradicting previous allegations that triazolam is more disruptive.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

18.

Comparison of oral triazolam and nitrous oxide with placebo and intravenous diazepam for outpatient premedication.

Author: KaufmanE, HargreavesK M, DionneR A

Anxiolytic effect
Dental sedation

Triazolam is a drug that is used to treat anxiety. This study found that triazolam was effective at reducing anxiety in dental patients, and caused less cognitive impairment than diazepam, another anxiety medication.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

19.

Differential effects of triazolam and ethanol on awareness, memory, and psychomotor performance.

Author: RoacheJ D, CherekD R, BennettR H, SchenklerJ C, CowanK A

Impairment of memory
Impairment of psychomotor performance

Triazolam and ethanol produced comparable degrees of impairment on psychomotor tasks, but triazolam had a greater effect on memory.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

20.

The effect of ingestion time interval on the interaction between itraconazole and triazolam.

Author: NeuvonenP J, VarheA, OlkkolaK T

Increased triazolam effects

Itraconazole interacts considerably with triazolam when this hypnotic agent is ingested within 24 hours after itraconazole.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

21.

Evaluation of zolpidem, triazolam, and placebo as hypnotic drugs the night before surgery.

Author: MorganP J, ChapadosR, ChungF F, GauthierM, KnoxJ W, Le LorierJ

Easier falling asleep
Improved sleep latency
Improved total sleep time
Reduced wakefulness

Zolpidem (10 mg) was as effective as triazolam (0.25 mg) in treating transient insomnia. Both drugs were more effective than placebo and were well tolerated.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

22.

Trazodone and triazolam: acute subject-rated and performance-impairing effects in healthy volunteers.

Author: RushC R, MadakasiraS, HayesC A, JohnsonC A, GoldmanN H, PazzagliaP J

Less performance impairing
Dizziness
Excitement
Itchy skin
Nervousness
Restlessness
Stomach turning

Trazodone was found to be a viable alternative to benzodiazepine hypnotics like triazolam, producing similar levels of sedation but with fewer performance-impairing effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

23.

Triazolam impairs delayed recall but not acquisition of various everyday memory tasks in humans.

Author: DavisC M, Ambros-IngersonJ, GrangerR, WuJ, ZabanehR, AbdelnabyM, LynchG

Enhanced immediate recall
Memory impairment

Triazolam was found to impair memory retention at delays ranging from 20 minutes to 1 week in 24 human subjects. While the drug did not impair recall of previously learned information, it did impair encoding of new information.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Language : English

24.

Effects of a small dose of triazolam on P300.

Author: HayakawaT, UchiyamaM, UrataJ, EnomotoT, OkuboJ, OkawaM

Cognitive dysfunction

Triazolam, a benzodiazepine, can cause cognitive dysfunction without general sedation or sleepiness.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

25.

Triazolam impairs inhibitory control of behavior in humans.

Author: FillmoreM T, RushC R, KellyT H, HaysL

Improved behavioral inhibition
Behavioral disinhibition

This study investigated the effects of triazolam, a sedative-hypnotic drug, on the ability to inhibit behavior in humans. Triazolam reduced response inhibitions, increased the time required to inhibit responses, and slowed the activation of responses, indicating its potential to produce behavioral disinhibition.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.