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Paper Details

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Paper Details

Treatment of Raynaud's syndrome with adrenergic alpha-blockade with or without beta-blockade.

Author: CleophasT J, FennisJ F, van 't LaarA, van LierH J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Alpha-blockade is effective in treating Raynaud's syndrome. Adding beta-blockade counteracts fluid retention and reduces heart rate, without causing hypotension.

Paper Details　

Original Abstract of the Article :

In a double blind placebo-controlled cross-over trial of 24 weeks 31 patients with Raynaud's syndrome were treated with the alpha-blocker phenoxybenzamine (10-20 mg daily) and with the combination of the alpha-blocker phenoxybenzamine (10-20 mg daily) and the beta-blocker sotalol (40-80 mg daily). A...See full text at original site

Dr.Camel's Paper Summary Blog

in preparation

Date :

Date Completed 1984-02-29
Date Revised 2017-02-14

Further Info :

Pubmed ID

DOI: Digital Object Identifier

10.1177/000331978403500104

Related Literature

Article Analysis

・Side Effects of phenoxybenzamine

SNS

PICO Info

in preparation

Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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