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Topical ether and herpes simplex labialis.
Author: GuinanM E, KernE R, MacCalmanJ, OverallJ C, SpruanceS L
Original Abstract of the Article :
In a double-blind, placebo-controlled study, 51 patients with recurrent herpes simplex labialis were treated with topical ether or placebo within 24 hours of onset of a lesion. There was no noteworthy difference between groups given ether and placebo in progression of lesions, healing time, duration...See full text at original site
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/6243714
データ提供:米国国立医学図書館(NLM)
Topical Ether: A Remedy for Herpes Simplex Labialis?
The realm of medicine is a vast desert, brimming with perplexing ailments, and herpes simplex labialis (HSV) is no exception. This study, a double-blind, placebo-controlled trial, ventured into this desert to assess the efficacy of topical ether as a treatment for HSV. They recruited 51 individuals suffering from this common condition and observed their response to ether or a placebo within 24 hours of the onset of a lesion. The results, however, were like a mirage - they found no significant difference between the two groups in terms of lesion progression, healing time, pain intensity, or viral shedding. The ether also failed to significantly reduce the viral load in the lesions. However, a surprising revelation emerged - a whopping 75% of patients receiving ether and 77% receiving the placebo reported a reduction in the severity and duration of their lesions. This remarkable placebo effect highlights the importance of objective measurements and the need for rigorous, placebo-controlled trials in medicine.
A Placebo Effect: A Powerful Mirage?
This study reveals a startling fact: the power of the placebo effect in treating recurrent herpes infection. Even though the ether showed no objective benefit, a significant number of participants in both groups reported positive results. This demonstrates the importance of subjective perception in the treatment experience and highlights the need for careful consideration of placebo effects in clinical trials.
A Lesson from the Desert: The Quest for Effective Treatments
This research serves as a reminder that, like the desert, the search for effective treatments can be riddled with false promises. While the ether failed to live up to its potential, it underscores the importance of rigorous research methodologies and the critical role of placebo-controlled trials in discerning true therapeutic efficacy. We must always remain vigilant, like travelers in the desert, to distinguish between genuine oases and fleeting mirages.
Dr.Camel's Conclusion
This study demonstrates the importance of rigorous research and the need to differentiate between true treatment effects and the powerful placebo effect. The desert of medical research is vast and full of surprises, and we must always proceed with caution, guided by objective evidence.
Date :
- Date Completed 1980-04-25
- Date Revised 2016-10-17
English
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