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Pivmecillinam plus pivampicillin in urinary tract infections: a randomized, open comparison with co-trimoxazole in hospitalized patients.

Author: RavnT J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Pivmecillinam/pivampicillin was more effective in treating complicated urinary tract infections than co-trimoxazole. Both treatments were well tolerated with no serious side effects.
Paper Details　
Original Abstract of the Article :
The efficacy and tolerance of a fixed-dose combination of 200 mg pivmecillinam and 250 mg pivampicllin was compared with that of co-trimoxazole (800 mg sulphamethoxazole plus 160 mg trimethoprim) in 42 hospital in-patients with complicated urinary tract infections. Patients received a 10-day course ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6267617

データ提供：米国国立医学図書館（NLM）

Comparing Pivmecillinam/Pivampicillin with Co-trimoxazole for Urinary Tract Infections

This study takes us on a journey through the world of urinary tract infections (UTIs), comparing the efficacy of two antibiotic treatments in hospitalized patients. Researchers conducted a randomized, open comparison study to evaluate the effectiveness of a fixed-dose combination of pivmecillinam and pivampicillin versus co-trimoxazole in treating UTIs. They analyzed the results to determine which treatment effectively eradicated the infections and provided relief to patients.

Pivmecillinam/Pivampicillin: A Promising Option

The study found that both treatments successfully eradicated the infecting organisms in a significant number of patients. However, pivmecillinam/pivampicillin demonstrated higher efficacy in eradicating UTIs, showing a success rate of 100% compared to 89% for co-trimoxazole. The study also highlighted the clinical response to the treatment, with pivmecillinam/pivampicillin showing better results in alleviating symptoms. These results suggest that pivmecillinam/pivampicillin may be a viable option for the treatment of UTIs in hospitalized patients.

Choosing the Right Antibiotic

This study offers valuable insights into the treatment of UTIs, particularly for patients who require hospitalization. It emphasizes the importance of choosing the right antibiotic for each patient based on the specific organism causing the infection and the individual's medical history. Just as a desert traveler chooses the most suitable route based on the terrain and weather conditions, healthcare professionals need to carefully select the right antibiotic for optimal outcomes.

Dr.Camel's Conclusion

This research highlights the importance of finding the most effective treatment for UTIs. Just as a desert oasis provides relief from the harsh conditions, the right antibiotic can provide a much-needed solution for patients battling these infections. The study underscores the value of comparing treatment options to find the most effective solution for each patient, taking into account individual factors and the specific type of infection.

Date :
  1. Date Completed 1981-10-25
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

6267617

DOI: Digital Object Identifier

6267617

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・Side Effects of pivmecillinam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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