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Pivmecillinam, co-trimoxazole and oral mecillinam in gastroenteritis due to Vibrio spp.

Author: ChristensenO, MendayP, PescanteM, SantiagoL, UylangcoC

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Antibacterial therapy with pivmecillinam or cotrimoxazole was significantly superior to rehydration alone in children with severe bacterial gastroenteritis. Both antibiotics were equally effective. No side effects were observed in any of the patients.
Paper Details　
Original Abstract of the Article :
The comparative efficacy of antibacterial therapy with pivmecillinam or cotrimoxazole and general supportive care only was studied in patients with severe bacterial gastroenteritis. Overall, treatment with antibiotics proved significantly superior to rehydration alone in 42 children. Active therapy ...See full text at original site
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引用元：
https://doi.org/10.1093/jac/13.2.171

データ提供：米国国立医学図書館（NLM）

Fighting Gastroenteritis: Antibiotics vs. Supportive Care

Gastroenteritis, or 'stomach flu,' is a common and often uncomfortable ailment. This study delves into the effectiveness of antibiotics in treating [gastroenteritis] caused by [Vibrio spp.], a type of bacteria. The researchers compared the outcomes of patients receiving antibiotic therapy with those receiving only [supportive care]. They found that [antibiotic therapy] was significantly more effective than [supportive care] alone in improving patient outcomes.

Pivmecillinam and Co-trimoxazole: Effective Antibiotics for Vibrio Gastroenteritis

This study evaluated the effectiveness of two specific antibiotics, [pivmecillinam] and [co-trimoxazole], in treating [Vibrio spp.] gastroenteritis. The researchers found that both antibiotics were equally effective in reducing symptoms and improving patient outcomes. This finding is particularly important because it provides clinicians with two viable treatment options for this specific type of gastroenteritis.

Staying Hydrated is Key, But Antibiotics Can Help

Imagine your gut as a vast desert landscape. When [Vibrio spp.] bacteria invade, it's like a sandstorm, causing havoc and discomfort. [Antibiotics] act like a calming breeze, dispersing the sandstorm and restoring balance. This study underscores the importance of staying hydrated during [gastroenteritis], but also shows that antibiotics can be a valuable tool in fighting specific types of bacterial infections.

Dr.Camel's Conclusion

This study emphasizes the importance of [antibiotic therapy] in managing [Vibrio spp.] gastroenteritis, particularly in cases where [supportive care] alone is insufficient. It also highlights the effectiveness of [pivmecillinam] and [co-trimoxazole] as viable treatment options. Remember, it's always essential to consult with a doctor for proper diagnosis and treatment, as they can guide you on the best course of action based on your specific situation.

Date :
  1. Date Completed 1984-05-02
  2. Date Revised 2019-05-11
Further Info :

Pubmed ID

6323378

DOI: Digital Object Identifier

10.1093/jac/13.2.171

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・Side Effects of pivmecillinam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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