Treatment of first episodes of genital herpes simplex virus infection with oral acyclovir. A randomized double-blind controlled trial in normal subjects.

Author: AcunaG, BrysonY J, CherryJ D, Creagh-KirkT, DillonM, GrowdonW, JohnsonB L, KeeneyR, LovettM, TaylorS, WiesmeierE

Paper Details 
Original Abstract of the Article :
We performed a double-blind placebo-controlled trial of oral acyclovir in the treatment of first episodes of genital herpes simplex virus infections in 48 young adults (31 women and 17 men). Subjects were randomized to receive either placebo or acyclovir (200 mg per dose) five times daily for 10 day...See full text at original site
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引用元:
https://doi.org/10.1056/NEJM198304213081602

データ提供:米国国立医学図書館(NLM)

Oral Acyclovir: An Effective Treatment for First-Episode Genital Herpes

This research explores the realm of [virology] and [pharmacology], investigating the effectiveness of [oral acyclovir] in treating [first-episode genital herpes simplex virus (HSV) infections]. The authors conducted a [double-blind placebo-controlled trial] to evaluate the efficacy of acyclovir in reducing viral shedding, lesion formation, and symptom severity. Their findings provide strong evidence for the effectiveness of acyclovir in managing initial genital HSV infections.

Acyclovir: A Powerful Weapon Against Genital Herpes

This study demonstrates the effectiveness of [oral acyclovir] in reducing [virus shedding, new lesion formation, and the duration of genital lesions] in patients with [first-episode genital HSV infections]. The authors observed a [significant reduction] in these measures in the acyclovir group compared to the placebo group, highlighting the value of acyclovir in managing initial HSV infections. This research underscores the importance of prompt and effective antiviral therapy in controlling HSV outbreaks.

Managing Genital Herpes: From Outbreak to Prevention

This research provides valuable insights into the management of [genital HSV infections], offering a [clinically effective] treatment option for [first-episode outbreaks]. While acyclovir is effective in reducing symptom severity and viral shedding, it does not prevent [latency or recurrences]. This research emphasizes the importance of [continued follow-up care] and [potential preventive measures] to manage HSV infections long-term.

Dr.Camel's Conclusion

Just like a camel facing the challenges of the desert, individuals grappling with genital HSV infections can feel overwhelmed and uncertain. This research offers a valuable tool for managing outbreaks, with oral acyclovir providing a potent weapon against this viral adversary. While it's important to understand the limitations of this treatment, it provides a crucial step in navigating the complex journey of managing HSV infections.

Date :
  1. Date Completed 1983-05-05
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6339923

DOI: Digital Object Identifier

10.1056/NEJM198304213081602

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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