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Clinical evaluation of choline magnesium trisalicylate in rheumatoid arthritis.

Author: ModyG M, NaidooP D, SinghT G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Choline magnesium trisalicylate (CMT) was effective in reducing inflammation in patients with rheumatoid arthritis. Tinnitus was the most common side effect, which resolved with dose reduction.
Paper Details　
Original Abstract of the Article :
Twenty-three patients with rheumatoid arthritis were given choline magnesium trisalicylate (CMT) (Trilisate; Adcock-Ingram) in a dose of 1.5 g (3 tablets) twice daily and were followed up for 6 weeks. Nineteen patients completed the study and the data obtianed were subjected to statistical analysis....See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6348967

データ提供：米国国立医学図書館（NLM）

Clinical Evaluation of Choline Magnesium Trisalicylate for Rheumatoid Arthritis

The treatment of rheumatoid arthritis, a debilitating autoimmune disease, is a challenging journey. This study evaluated the effectiveness of choline magnesium trisalicylate (CMT) in managing rheumatoid arthritis. The authors explored the potential of CMT as a treatment option for patients, hoping to discover a new oasis in the vast desert of rheumatoid arthritis treatment.

CMT's Potential to Reduce Inflammation

The researchers observed a statistically significant improvement in the indices of inflammation in patients treated with CMT. This finding suggests that CMT may have a beneficial effect on reducing inflammation, a hallmark of rheumatoid arthritis. This is like finding a cool spring in the desert, offering a soothing respite from the heat and discomfort of the disease.

Potential Benefits and Side Effects

While CMT showed promise in reducing inflammation, the study also identified potential side effects, including tinnitus, pruritus, and minor gastrointestinal issues. This highlights the need for further research to optimize CMT dosage and minimize side effects. This is like navigating a desert landscape, carefully considering the risks and benefits of each path and choosing the safest and most effective route.

Dr. Camel's Conclusion

This study provides valuable insights into the potential of CMT as a treatment option for rheumatoid arthritis. However, it also underscores the need for further research to understand the optimal dosage and the potential risks associated with CMT. As with navigating any challenging terrain, a thorough understanding of the risks and benefits is essential for achieving a safe and effective journey.
Date :
  1. Date Completed 1983-09-09
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

6348967

DOI: Digital Object Identifier

6348967

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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