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Double-blind comparative study of two dosage regimens of cefaclor and amoxicillin-clavulanic acid in the outpatient treatment of soft tissue infections.

Author: PienF D

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cefaclor and amoxicillin-clavulanic acid were both effective in treating soft tissue infections (cure rates 64%–85%), but amoxicillin-clavulanic acid caused more gastrointestinal issues.
Paper Details　
Original Abstract of the Article :
A total of 88 patients were enrolled in a double-blind comparison of cefaclor and amoxicillin-clavulanic acid for the outpatient treatment of soft tissue infections (abscesses, cellulitis, and impetigo). In 84 clinically evaluable patients, high cure rates were obtained for all treatment groups (64 ...See full text at original site
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引用元：
https://doi.org/10.1128/AAC.24.6.856

データ提供：米国国立医学図書館（NLM）

Comparing Cefaclor and Amoxicillin-Clavulanic Acid for Treating Soft Tissue Infections

This research compares the [Efficacy] of [Cefaclor] and [Amoxicillin-Clavulanic Acid] in treating [Soft Tissue Infections]. It uses a [Double-Blind Comparative Study] to assess [Clinical Cure Rates] and [Gastrointestinal Side Effects]. The authors demonstrate [High Cure Rates] for both treatments but [Higher Incidence of Gastrointestinal Side Effects] with Amoxicillin-Clavulanic Acid. This study highlights the [Importance of Considering Side Effects] when choosing antibiotics for soft tissue infections.

Cefaclor: A Safe and Effective Alternative for Soft Tissue Infections

This research reveals that [Cefaclor is a viable alternative] to [Amoxicillin-Clavulanic Acid] for treating soft tissue infections. The study found that [Cefaclor resulted in comparable cure rates] with [Fewer gastrointestinal side effects], suggesting its potential as a safer option for some patients. This finding provides valuable information for healthcare providers to make informed treatment decisions.

Navigating the Complex World of Antibiotics

This research emphasizes the [Importance of individualizing antibiotic therapy] to minimize side effects and optimize treatment outcomes. It highlights the [Need to consider patient factors] such as [Previous antibiotic use and gastrointestinal sensitivity] when choosing an antibiotic. This study underscores the importance of ongoing research to develop new antibiotics with improved safety profiles.

Dr. Camel's Conclusion

This research offers valuable insights into the treatment of soft tissue infections. Just as a camel navigates the diverse landscapes of the desert, this study guides us through the complexities of antibiotic therapy. It highlights the importance of considering patient factors and choosing antibiotics with optimal safety and efficacy profiles. This study encourages us to remain vigilant in our pursuit of safer and more effective treatments for common infections.

Date :
  1. Date Completed 1984-02-24
  2. Date Revised 2021-05-26
Further Info :

Pubmed ID

6362559

DOI: Digital Object Identifier

10.1128/AAC.24.6.856

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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