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Treatment of recurrent genital herpes simplex infections with oral acyclovir. A controlled trial.

Author: BadgerG J, BrysonY, ConnorJ D, CoreyL, MertzG J, OxmanM N, RedfieldD, ReichmanR C, RichmanD D, SavoiaM C

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Oral acyclovir effectively shortened the duration of virus shedding and healing time in patients with recurrent genital herpes. Self-initiated therapy early in the course of a recurrent episode showed even greater benefits.
Paper Details　
Original Abstract of the Article :
Two hundred fifty patients were entered into a multicenter trial to evaluate the efficacy and toxicity of orally administered acyclovir for treatment of recurrent genital herpes. The study consisted of part A, in which patients entered the study within 48 hours of the onset of lesions, and part B, i...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6368877

データ提供：米国国立医学図書館（NLM）

Treating Recurrent Genital Herpes with Oral Acyclovir

This research delves into the fascinating world of antiviral treatments, specifically investigating the efficacy of oral acyclovir in managing recurrent genital herpes. The study involved 250 participants, a veritable caravan of individuals, who bravely ventured into the realm of clinical trials. These intrepid explorers were divided into two groups, one receiving acyclovir and the other a placebo, with each group further divided into two sub-groups based on their treatment initiation timing. Through meticulous observation, researchers discovered that acyclovir significantly shortened the duration of virus shedding and the healing time for lesions, especially when therapy was self-initiated early in the course of an outbreak.

Acyclovir's Impact on Herpes Shedding

The results of this trial suggest that acyclovir, much like a calming oasis in the midst of a scorching desert, effectively shortens the duration of virus shedding and the duration of lesions in patients suffering from recurrent genital herpes. The self-initiated approach, where patients take control of their treatment early on, seems to be like a well-timed caravan setting out on a journey – it helps them reach their destination, a faster recovery, more efficiently.

Keeping Herpes at Bay: A Personal Journey

This study emphasizes the importance of taking proactive measures against recurrent genital herpes, much like a wise traveler anticipating the desert's challenges. Early treatment initiation, like a strategic camel caravan, is vital in minimizing the duration of symptoms and potentially improving overall health.

Dr.Camel's Conclusion

This research sheds light on the effectiveness of acyclovir in combating recurrent genital herpes, particularly when utilized in a timely manner. It highlights the importance of patient empowerment and self-management in achieving optimal health outcomes, much like a skilled caravan leader guiding their group through the desert. While more research is needed, this study offers hope and potential strategies for managing this challenging condition.

Date :
  1. Date Completed 1984-05-10
  2. Date Revised 2016-10-17
Further Info :

Pubmed ID

6368877

DOI: Digital Object Identifier

6368877

Related Literature

Article Analysis
・Effective treatment of genital herpes
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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