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Comparative study of cimetidine and trimipramine in the short-term treatment of duodenal and gastric ulcer.
Author: ArvaP, LarsenS, MyrenJ, ValnesK, WetterhusS
Original Abstract of the Article :
Sixty-nine outpatients with endoscopically confirmed duodenal and prepyloric (DU) or gastric ulcers (GU) completed a 4-week double-blind trial with either cimetidine, 1 g/day, or trimipramine, 50 mg/day. Ulcer healing was assessed by endoscopy at 4 weeks. At the end of the study 14 of 23 patients wi...See full text at original site
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引用元:
https://doi.org/10.3109/00365528309181555
データ提供:米国国立医学図書館(NLM)
A Tale of Two Ulcer Treatments: Cimetidine vs. Trimipramine
Peptic ulcers, a common ailment affecting the digestive system, often cause pain and discomfort. This study aimed to compare the effectiveness of two different medications, cimetidine and trimipramine, in treating duodenal and gastric ulcers.
The researchers conducted a double-blind clinical trial involving 69 patients with endoscopically confirmed ulcers. Participants were randomly assigned to receive either cimetidine or trimipramine for a four-week period. The researchers carefully assessed ulcer healing rates and symptom improvement at the end of the trial.
The findings revealed that both cimetidine and trimipramine demonstrated significant symptom improvement and a reduction in pain attacks. While there was no statistically significant difference in ulcer healing rates between the two groups, the study suggests that trimipramine may be a viable alternative to cimetidine for treating duodenal and potentially gastric ulcers.
A New Oasis in the Desert of Ulcer Treatment
The study found that both cimetidine and trimipramine were effective in alleviating symptoms and reducing pain associated with ulcers. This research highlights the importance of personalized treatment options, considering individual responses and preferences.
A New Oasis in the Desert of Ulcer Treatment
Experiencing symptoms of ulcers can be a challenging experience. It is crucial to consult with a healthcare professional to obtain a proper diagnosis and receive appropriate treatment. Just as a camel needs to find a reliable source of water in a harsh desert, individuals experiencing digestive discomfort should seek guidance from a knowledgeable physician.
Dr.Camel's Conclusion
This study provides valuable insights into the comparative effectiveness of cimetidine and trimipramine in treating peptic ulcers. While both medications demonstrated symptom improvement, the study suggests that trimipramine may be a viable alternative to cimetidine. This research underscores the importance of individualized treatment plans, tailored to meet the unique needs of each patient.
Date :
- Date Completed 1984-05-30
- Date Revised 2019-08-14
Further Info :
Related Literature
English
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