Safety and efficacy of bupropion in elderly patients: preliminary observations.

Author: BorensteinM, ColeK, HowardA, KaneJ M, SarantakosS

Paper Details 
Original Abstract of the Article :
The efficacy and safety of bupropion, an atypical antidepressant, were assessed in depressed patients aged 55 and above. Data were analyzed for 38 patients who completed 4 weeks of double-blind treatment with bupropion in maximum doses of 150 or 450 mg/day; imipramine, up to 200 mg/day; or placebo. ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/6406442

データ提供:米国国立医学図書館(NLM)

Safety and Efficacy of Bupropion in Elderly Patients

This research investigates the effectiveness and safety of bupropion, an atypical antidepressant, in treating depression in older adults. The study utilized a double-blind, randomized controlled trial design to compare bupropion, imipramine, and a placebo in 38 patients aged 55 and above. Preliminary results suggest that bupropion exhibits antidepressant activity and is well-tolerated in this population. Additionally, the study highlights a potential advantage of bupropion regarding cardiovascular side effects.

Bupropion: A Promising Antidepressant for Elderly Patients

This study provides encouraging evidence that bupropion could be a viable treatment option for depression in older adults. The findings suggest that bupropion not only effectively alleviates depressive symptoms but also carries a favorable safety profile, particularly concerning cardiovascular risks. This is significant considering the increased vulnerability of elderly patients to heart-related conditions.

Navigating the Depths of Depression in the Elderly

The study's findings are like a refreshing oasis in the often-dry landscape of depression treatment for the elderly. It demonstrates that bupropion can offer a safe and effective path to recovery for older individuals battling depression. Just as a camel relies on an oasis for sustenance and respite during its desert journey, elderly patients can find relief and renewed hope in this promising treatment option.

Dr.Camel's Conclusion

The study provides hope for older individuals struggling with depression by suggesting that bupropion could be an effective and well-tolerated treatment option. These findings underscore the importance of individualized approaches to managing depression in the elderly, acknowledging the unique needs and vulnerabilities of this population.

Date :
  1. Date Completed 1983-07-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6406442

DOI: Digital Object Identifier

6406442

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.