Paper Details 
Original Abstract of the Article :
A comparative trial was carried out in 4 orphanges in Seoul, to compare the anthelminthic efficacy of oxantel-pyrantel suspension and mebendazole tablets against mixed infections of Ascaris lumbricoides and Trichuris trichiura. 40 patients were divided into 4 groups and received oxantel-pyrantel sus...See full text at original site
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引用元:
https://doi.org/10.2165/00003495-197800151-00018

データ提供:米国国立医学図書館(NLM)

Oxantel-pyrantel vs. Mebendazole: A Head-to-Head Showdown in the Desert of Helminth Infections

In the vast and sandy landscape of parasitic infections, helminths pose a significant challenge. This study compares the effectiveness of two anthelminthic drugs, oxantel-pyrantel suspension and mebendazole tablets, against mixed infections of Ascaris lumbricoides and Trichuris trichiura. The researchers conducted a comparative trial in four orphanages in Seoul, utilizing a rigorous methodology and a large sample size. The results demonstrate that both drugs achieved a 100% cure rate for Ascaris infections. However, oxantel-pyrantel exhibited a superior cure rate and egg reduction rate against Trichuris infections, suggesting its potential as a more effective treatment for mixed infections.

Oxantel-pyrantel: A Victor in the Battle Against Mixed Helminth Infections

The study's findings clearly indicate that oxantel-pyrantel emerges as the victor in the treatment of mixed Ascaris and Trichuris infections. The 100% cure rate for Ascaris and the significantly higher cure rate and egg reduction rate for Trichuris compared to mebendazole underscore its effectiveness. These results hold significant implications for the management of helminth infections, particularly in areas with high prevalence rates.

Oxantel-pyrantel: A New Oasis in the Desert of Helminth Infections

The study's findings offer a valuable insight into the effectiveness of oxantel-pyrantel in combating mixed helminth infections. This knowledge can be used to guide treatment decisions and optimize patient outcomes. However, it is important to remember that the desert of parasitic infections is vast and complex, requiring a multi-faceted approach that includes preventive measures, sanitation initiatives, and continued research to develop new and more effective treatments.

Dr.Camel's Conclusion

This study provides a clear and concise comparison of two anthelminthic drugs, offering valuable insights into the treatment of mixed helminth infections. While oxantel-pyrantel emerges as a more effective treatment, it is essential to continue exploring new approaches and tackling the challenges posed by these persistent parasites. As a seasoned desert traveler, I understand the importance of adaptability and innovation in navigating the ever-changing landscape of parasitic infections.

Date :
  1. Date Completed 1978-08-28
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

657997

DOI: Digital Object Identifier

10.2165/00003495-197800151-00018

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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