Tolerance to amoxapine antidepressant effects.

Author: AdenG, MoldawskyR, ZetinM

Paper Details 
Original Abstract of the Article :
Several patients treated with amoxapine (in dosages ranging from 50 to 300 mg/day) had excellent initial responses fo...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6627290

データ提供:米国国立医学図書館(NLM)

Tolerance to Amoxapine's Antidepressant Effects: A Challenge in Treatment

This research explores the complex world of [pharmacology] and examines the phenomenon of tolerance to amoxapine, an antidepressant medication. The study observed that some patients experienced excellent initial responses to amoxapine, only to relapse later, despite dose adjustments. This suggests that the body can develop a tolerance to the drug's antidepressant effects, posing a challenge for treatment. This research highlights the importance of understanding and managing tolerance to medications in order to ensure optimal treatment outcomes.

The Development of Drug Tolerance

The study's findings suggest that the development of tolerance to amoxapine's antidepressant effects can be a significant obstacle in treatment. This phenomenon occurs when the body becomes accustomed to a medication over time, requiring higher doses to achieve the same therapeutic effect. Tolerance can lead to treatment failure and can necessitate adjustments in medication regimens.

A Reminder of Treatment Complexity

This research underscores the complex nature of drug treatment and the need for careful monitoring and adjustments. Tolerance to medications can be a common phenomenon, and it is crucial for healthcare providers to be aware of this potential challenge. This knowledge is essential for ensuring that patients receive the most effective and personalized care.

Dr.Camel's Conclusion

Like a camel traversing a vast and unforgiving desert, navigating the complexities of drug treatment can be a challenging journey. This research highlights the importance of understanding and managing tolerance to medications. It reminds us that the path to effective treatment is not always straightforward and requires careful attention to individual responses and potential drug interactions. A collaborative approach between patients and their healthcare providers is essential to ensure the best possible outcomes.

Date :
  1. Date Completed 1983-12-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6627290

DOI: Digital Object Identifier

6627290

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