Pressure and humoral changes induced by atenolol and hydrochlorothiazide + amiloride, alone and in free combination. A comparative between-patient study.

Author: GalliF, PiazzaV, SalvadeoA, SegagniS, VillaG

Paper Details 
Original Abstract of the Article :
The authors have performed a between-patient study in 76 patients with mild or moderate essential arterial hypertension, with the aim of comparing the results of atenolol 100 mg daily, hydrochlorothiazide 50 mg + amiloride 5 mg 1 tablet daily, and the combination of the above two agents at the same ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/6678831

データ提供:米国国立医学図書館(NLM)

Exploring the Synergy of Blood Pressure Medications: A Desert Oasis of Cardiovascular Health

This study investigates the effects of atenolol, hydrochlorothiazide + amiloride, and their combination on blood pressure and humoral changes in patients with mild or moderate essential arterial hypertension. The researchers, like astute desert explorers analyzing the impact of different water sources, aimed to compare the efficacy and safety of these medications in managing hypertension. This research is like seeking a balanced approach to navigating the complex desert terrain of cardiovascular health, exploring the interplay between different therapeutic strategies.

A Harmonious Blend for Blood Pressure Control

The study found that the combination therapy of atenolol and hydrochlorothiazide + amiloride provided effective and well-tolerated blood pressure control in most patients, including those who did not respond to single-agent therapy. This synergistic effect, like combining the strengths of different water sources to create a thriving oasis, highlights the potential for combining medications to optimize treatment outcomes. The findings suggest that this combination therapy may be a valuable tool for managing hypertension, offering a more comprehensive approach to addressing this prevalent condition.

Navigating the Desert of Hypertension: A Guide for Healthcare Professionals

This study provides valuable insights for healthcare professionals, guiding them in their selection and management of blood pressure medications. The findings emphasize the potential benefits of combining different drug classes to achieve optimal blood pressure control and minimize potential side effects. It's like equipping a camel caravan with a diverse array of tools and knowledge to navigate the challenging desert landscape of hypertension management.

Dr.Camel's Conclusion

This study demonstrates the efficacy and safety of combining atenolol and hydrochlorothiazide + amiloride for managing blood pressure in patients with mild or moderate essential arterial hypertension. The findings offer valuable insights for healthcare professionals, highlighting the potential for synergistic effects and improved patient outcomes when combining different medications. It's a testament to the ongoing quest for effective and well-tolerated treatment strategies in the desert of cardiovascular health, reminding us that sometimes the most effective solutions lie in finding harmony between different approaches.

Date :
  1. Date Completed 1984-09-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6678831

DOI: Digital Object Identifier

6678831

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.